Dapoxetine Impurity 44 CAS 623-71-2
| CAS No. | 623-71-2 |
| Molecular Formula | C5H9ClO2 |
| Molecular Weight | 136.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dapoxetine Impurity 44 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Dapoxetine Impurity 44 (CAS 623-71-2) is a certified pharmaceutical impurity reference standard with the molecular formula C5H9ClO2 and a molecular weight of 136.58 g/mol.
Dapoxetine Impurity 44 (C5H9ClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H9ClO2 |
| Molecular Weight | 136.58 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Dapoxetine Standards
- Dapoxetine Impurity 21 (CAS 2941-20-0)
- Dapoxetine Impurity N3 (CAS 4436-22-0)
- Dapoxetine Impurity 84 (CAS 4436-23-1)
- Dapoxetine Impurity 90 (CAS CATO-C4X-143990)
- Dapoxetine Impurity 48 (Contains ~1% BHT as stabilizer) (CAS 768-03-6)
- Dapoxetine Impurity 23 (CAS 102-93-2)
- Dapoxetine Impurity 45 (CAS 691-93-0)
- Dapoxetine Impurity 43 (CAS 6001-87-2)
Recommended Standards
- Chlorpromazine Impurity 19 (CAS CATO-C4X-142119)
- 2-Chloropropionic Acid-Ethyl Ester (CAS 535-13-7)
- Promethazine Impurity 71 (CAS CATO-C4X-141871)
- (1R,2R)-1-Chloro-2-Fluorocyclohexane (CAS 4536-11-2)
- Dacomitinib Impurity 4 (CAS 179552-75-1)
- Nicardipine Impurity 52 (CAS 182798-71-6)
- Pazufloxacin Impurity 5 (CAS 176760-98-8)
- 1-(2-Fluorobenzyl)-1h-1,2,3-triazol-4-amine (CAS 1443291-34-6)
- D-Sorbitol hexaacetate (CAS 7208-47-1)
- 6-Chloro-1-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1150618-33-9)
- 2-Oxo-2-((7-oxocyclohepta-1,3,5-trien-1-yl)amino)acetic acid (CAS 65425-79-8)
- Zuranolone impurity 1 (CAS CATO-C4X-30381)
- Methyl 2-bromo-3-cyano-5-formylbenzoate (CAS 1805407-11-7)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com