6-(Furan-2-yl)-2-((pyridin-2-ylmethyl)thio)-4-(trifluoromethyl)nicotinonitrile CAS 625369-84-8
| CAS No. | 625369-84-8 |
| Molecular Formula | C17H10F3N3OS |
| Molecular Weight | 361.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-(Furan-2-yl)-2-((pyridin-2-ylmethyl)thio)-4-(trifluoromethyl)nicotinonitrile is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-(Furan-2-yl)-2-((pyridin-2-ylmethyl)thio)-4-(trifluoromethyl)nicotinonitrile (CAS 625369-84-8) is a high-purity analytical reference standard with the molecular formula C17H10F3N3OS and a molecular weight of 361.34 g/mol.
The molecular framework of 6-(Furan-2-yl)-2-((pyridin-2-ylmethyl)thio)-4-(trifluoromethyl)nicotinonitrile (C17H10F3N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-(Furan-2-yl)-2-((pyridin-2-ylmethyl)thio)-4-(trifluoromethyl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H10F3N3OS |
| Molecular Weight | 361.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Furan Standards
- 6-(Furan-2-yl)-2-((pyridin-4-ylmethyl)thio)-4-(trifluoromethyl)nicotinonitrile (CAS 625369-85-9)
- 4,4'-(Furan-2,5-diyl)bis(N-ethylbenzimidamide) (CAS 199919-01-2)
- N-(6-((4-((Furan-2-ylmethyl)amino)-4-oxobutyl)thio)pyridazin-3-yl)cyclopropanecarboxamide (CAS 1040648-11-0)
- 1-{2-[7-(furan-2-yl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-2,5-dimethyl-1H-pyrrole (CAS 861209-14-5)
- 2-((4-Ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-fluoro-4-methylphenyl)acetamide (CAS 585562-20-5)
- Ethyl 4-(2-(3-(furan-2-yl)-6-oxopyridazin-1(6H)-yl)acetyl)piperazine-1-carboxylate (CAS 1210500-14-3)
- 4-(Furan-2-carbonyl)-3-hydroxy-1-(pyridin-2-yl)-5-(p-tolyl)-1,5-dihydro-2H-pyrrol-2-one (CAS 380202-27-7)
- 2-[3,5-Bis(furan-2-carbonyl)benzoyl]furan (CAS 16801-56-2)
Recommended Standards
- (3-Amino-6-ethyl-5-methyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carbonyl)glycine (CAS 923553-63-3)
- (2S)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4,4-difluoro-Butanoic acid (CAS 467442-21-3)
- BMS-986235 (CAS 2253947-47-4)
- (2R,3S,4R,5R,6R)-5-acetamido-2-(acetoxymethyl)-6-methoxytetrahydro-2H-pyran-3,4-diyl diacetate (CAS 2771-48-4)
- 1-(2-Bromophenyl)-1h-imidazol-2-amine (CAS 1695937-66-6)
- 2-((4-Fluorophenyl)amino)-2-oxoacetic acid (CAS 69066-43-9)
- 1-ACetyl-4-(2-bromoethyl)piperazine hydrobromide (CAS 696623-56-0)
- Benzyl (S)-(4-chloro-1-(4-fluorophenyl)-3-oxobutan-2-yl)carbamate (CAS 400771-48-4)
- Bumetanide Impurity 12 (CAS 22893-29-4)
- 6-Chloro-alpha-(trifluoromethyl)pyridine-3-methanol (CAS 150698-77-4)
- 2-Methyl-3-oxoisoindoline-4-carbonitrile (CAS 1217709-41-5)
- (R)-1-(2-Chloro-6-methylpyrimidin-4-yl)pyrrolidin-3-ol, 95% (CAS 1261234-21-2)
- 1-[(3-Iodophenyl)carbonyl]pyrrolidine (CAS 349118-15-6)
- Endo-Ala35-Tirzepatide (CAS CATO-CPTD788687)
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