4-Chloro-6-(pyrrolidin-1-yl)pyrimidin-5-amine CAS 626217-76-3
| CAS No. | 626217-76-3 |
| Molecular Formula | C8H11ClN4 |
| Molecular Weight | 198.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-6-(pyrrolidin-1-yl)pyrimidin-5-amine.
4-Chloro-6-(pyrrolidin-1-yl)pyrimidin-5-amine (CAS 626217-76-3) is a high-purity analytical reference standard with the molecular formula C8H11ClN4 and a molecular weight of 198.65 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 4-Chloro-6-(pyrrolidin-1-yl)pyrimidin-5-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 198.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-6-(pyrrolidin-1-yl)pyrimidin-5-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H11ClN4 |
| Molecular Weight | 198.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-4-(isopropylamino)nicotinaldehyde (CAS 1012880-02-2)
- 2-Chloro-6-(cyclopentyloxy)pyrazine (CAS 1016697-18-9)
- 3-Chloro-5-(methylsulfonyl)-1,2,4-thiadiazole (CAS 10191-91-0)
- 5-Chloro-6-methyl-3-(pyrrolidin-1-yl)-1,2,4-triazine (CAS 1023818-03-2)
- Methyl 2-(5-chloro-2-methylphenyl)acetate (CAS 1076191-96-2)
- Methyl (2-chloro-6-methylphenyl)acetate (CAS 1076192-08-9)
- 3-(4-Chloro-3-methylphenyl)propanoic acid (CAS 1086386-05-1)
- 2-Chloro-N-ethyl-N-methylnicotinamide (CAS 112006-59-4)
Recommended Standards
- 4-chloro-6-(pyrrolidin-1-yl)pyrimidin-2-amine (CAS 263276-45-5)
- 4-Chloro-N-isopropylpicolinamide (CAS 604813-08-3)
- 4-Chloro-6-(piperazin-1-yl)pyrimidine (CAS 373356-50-4)
- 4-Chlorothiazole-2-sulfonamide (CAS 89501-94-0)
- 5-Bromo-N-(dicyclopropylmethyl)nicotinamide (CAS 1088181-43-4)
- 4-Methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline-9-carbaldehyde (CAS 1019108-33-8)
- Ethyl 7-chlorobenzofuran-2-carboxylate (CAS 260273-62-9)
- 3-Amino-2-phenylquinazolin-4(3H)-one (CAS 1904-60-5)
- 1-Hydroxy-3-(4-methoxybenzyl)guanidine (CAS 209673-05-2)
- Relebactam Impurity 67 (CAS CATO-C4X-214467)
- 1-(4-Methoxyphenyl)-2-((5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl)thio)ethan-1-one (CAS 326020-79-5)
- 4-(3-(1-Ethylpiperidin-2-yl)pyridin-2-yl)morpholine (CAS 1352534-23-6)
- 5-Bromo-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 1337532-51-0)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
Why CATO?
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