Riociguat Impurity 41 CAS CATO-C4X-174941
| CAS No. | CATO-C4X-174941 |
| Molecular Formula | C19H18FN9O |
| Molecular Weight | 407.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Riociguat Impurity 41 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 407.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Riociguat Impurity 41 (CAS CATO-C4X-174941) is a certified pharmaceutical impurity reference standard with the molecular formula C19H18FN9O and a molecular weight of 407.40 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H18FN9O |
| Molecular Weight | 407.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 9 |
Related Riociguat Standards
- Riociguat Impurity 36 (CAS CATO-C4X-174936)
- Riociguat EP Impurity A (CAS 625115-52-8)
- Riociguat EP Impurity B (CAS 3052969-92-0)
- Riociguat Impurity 18 (CAS 1361569-23-4)
- Riociguat Impurity 21 (CAS CATO-C4X-174921)
- Riociguat impurity 27 (CAS CATO-C4X-174927)
- Riociguat Impurity 11 (CAS CATO-C4X-174911)
- Riociguat Impurity 12 (CAS CATO-C4X-174912)
Recommended Standards
- 2-Fluoro-N-(5-((4-nitrophenyl)sulfonyl)thiazol-2-yl)benzamide (CAS 325720-29-4)
- (3S,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone (CAS 1478664-17-3)
- Omeprazole Acid Impurity (CAS 120003-72-7)
- 2-((3-Cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio)-N-(2-methoxyphenyl)acetamide (CAS 626222-12-6)
- Empagliflozin impurity 216 (CAS CATO-C4X-1065216)
- Terbutaline Impurity 25 (CAS 2352882-26-7)
- Venetoclax Impurity 58 (CAS CATO-C4X-249558)
- 3-Methyl-4-(pyridazin-3-yloxy)aniline (CAS 871020-44-9)
- Famphur Impurity 5 (CAS 3078-97-5)
- n-(4-Methylpiperidin-3-yl)acetamide (CAS 1283311-80-7)
- Methyl 5-amino-2-phenyl-2h-1,2,3-triazole-4-carboxylate (CAS 405279-31-4)
- 6-(4-Hydroxyphenyl)nicotinic acid (CAS 144289-96-3)
- Methyl(([1-(2,2,2-trifluoroethyl)-1h-pyrazol-3-yl]methyl))amine (CAS 1345510-65-7)
- Neuropeptide Y (1-24) amide (human, rat) (CAS 131448-51-6)
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