2-(4-Acetamidophenyl)-N-(6-amino-1-butyl-3-(3-fluorobenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetamide CAS 628279-20-9
| CAS No. | 628279-20-9 |
| Molecular Formula | C25H28FN5O4 |
| Molecular Weight | 481.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 481.52 g/mol gives 2-(4-Acetamidophenyl)-N-(6-amino-1-butyl-3-(3-fluorobenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(4-Acetamidophenyl)-N-(6-amino-1-butyl-3-(3-fluorobenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetamide (CAS 628279-20-9), molecular formula C25H28FN5O4 and molecular weight 481.52 g/mol, is a CATO reference standard with documented purity and traceability.
2-(4-Acetamidophenyl)-N-(6-amino-1-butyl-3-(3-fluorobenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetamide (C25H28FN5O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Acetamidophenyl)-N-(6-amino-1-butyl-3-(3-fluorobenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H28FN5O4 |
| Molecular Weight | 481.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Acetamidophenyl Standards
- N-(4-Acetamidophenyl)-2-{[3-methyl-7-(4-methylphenyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide (CAS 1040631-86-4)
- N-(4-acetamidophenyl)-2-((3-ethyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040661-73-1)
- N-(4-(4-Acetamidophenyl)thiazol-2-yl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-oxopyrrolidine-3-carboxamide (CAS 790237-66-0)
- 2-(3-((2-((3-Acetamidophenyl)amino)-2-oxoethyl)sulfonyl)-1H-indol-1-yl)-N,N-diethylacetamide (CAS 878056-95-2)
- 3-Acetamidophenyl 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}benzene-1-sulfonate (CAS 338414-10-1)
- 4-Acetamidophenyl 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}benzene-1-sulfonate (CAS 338400-17-2)
- N-(4-Acetamidophenyl)-2-((4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477329-08-1)
- N-(4-Acetamidophenyl)indomethacin Amide (CAS 261766-23-8)
Recommended Standards
- 2-(2-(Diphenylphosphino)phenyl)-4,5-diphenyloxazole (CAS 2757082-54-3)
- 4-(4-Methoxyphenyl)-2-((2-(4-nitrophenyl)-2-oxoethyl)thio)-6-phenylnicotinonitrile (CAS 332053-66-4)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(sulfomethyl)phenyl)propanoic acid (CAS 206060-45-9)
- 5,5-Dimethyl-2-oxotetrahydrofuran-3-carboxylic acid (CAS 50598-41-9)
- Methyl 4-chloro-5-methoxybenzo[b]thiophene-2-carboxylate (CAS 41280-83-5)
- 2,3-Bis(trifluoromethyl)pyrazolo[1,5-a]pyridine (CAS 73883-19-9)
- 2-(4-Methylpiperidin-1-yl)acetic acid (CAS 511237-54-0)
- Tert-butyl (5-(hydroxy((3-hydroxy-2,3-dimethylbutan-2-yl)oxy)boranyl)-4-methylpyridin-2-yl)carbamate (CAS 2246719-95-7)
- Ondansetron EP Impurity A (CAS 153139-56-1)
- 2-(Adamantan-1-yl)-2-aminoethanol (CAS 111749-17-8)
- Benzyl (3r,4r)-3,4-difluoropyrrolidine-1-carboxylate (CAS 790658-58-1)
- (2R,4R)-4-Allyl-5-oxopyrrolidine-2-carboxylic acid (CAS 402579-26-4)
- 4-Methoxy-6-(pyridin-4-yl)pyrimidine (CAS 53345-66-7)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
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