6-Chloro-2-(methylthio)pyrimidine-4-carboxamide CAS 6301-33-3
| CAS No. | 6301-33-3 |
| Molecular Formula | C6H6ClN3OS |
| Molecular Weight | 203.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Chloro-2-(methylthio)pyrimidine-4-carboxamide (C6H6ClN3OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
6-Chloro-2-(methylthio)pyrimidine-4-carboxamide (CAS 6301-33-3) is a high-purity analytical reference standard with the molecular formula C6H6ClN3OS and a molecular weight of 203.65 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Chloro-2-(methylthio)pyrimidine-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6ClN3OS |
| Molecular Weight | 203.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-chloro-1,3-dihydro-2$l^{6},1-benzothiazole-2,2-dione (CAS 111248-90-9)
- 6-chloro-1,3-dihydro-2$l^{6},1-benzothiazole-2,2-dione (CAS 111248-91-0)
- 5-chloro-1,3-dihydro-2$l^{6},1-benzothiazole-2,2-dione (CAS 111310-59-9)
- 5-chloro-6-(methylthio)nicotinic acid (CAS 1184743-95-0)
- 1-Chloro-4-(methylsulfanyl)-2-nitrobenzene (CAS 1199-36-6)
- 6-chloro-2-(methylsulfanyl)pyridine-3-carboxylic acid (CAS 1343727-62-7)
- 5-Chloro-2-(methylthio)isonicotinic acid (CAS 1596116-38-9)
- 2-Chloro-5-cyclopropylthiazole-4-carboxylic acid (CAS 1783543-40-7)
Recommended Standards
- 5-Chloro-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide (CAS 2515-75-5)
- n-(2-Chloroacetyl)thiophene-2-carboxamide (CAS 851176-02-8)
- 5-Chloro-2-(methylthio)pyrimidine-4-carboxamide (CAS 902243-56-5)
- 8-Chloro-7-fluoro-3,4-dihydro-2H-benzo[b][1,4]thiazine (CAS 101337-96-6)
- 4-Bromo-2-(diethylamino)benzaldehyde (CAS 1099629-82-9)
- 2-[5-methyl-3-(trifluoromethyl)-1h-pyrazol-1-yl]butanoic acid (CAS 1006348-57-7)
- N-(4-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine (CAS 296234-42-9)
- 2-Fluorobenzimidamide Hydrochloride (CAS 57075-81-7)
- N-Benzyl-3,5,6-trifluoropyridin-2-amine (CAS 189281-25-2)
- 2-Chloro-N-(4-fluorobenzyl)-N-isopropylacetamide (CAS 1175743-62-0)
- (4-(Difluoromethyl)-3-fluorophenyl)(pyridin-4-yl)methanone (CAS 1261588-69-5)
- Benoxaprofen-13C,d3 (CAS 1329840-53-0)
- Methyl 4-((2-nitro-4-(trifluoromethyl)phenyl)amino)butanoate (CAS 339101-25-6)
- Semaglutide Impurity 13 (CAS CATO-C4X-222613)
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