Terazosin EP Impurity N CAS 63074-07-7
| CAS No. | 63074-07-7 |
| Molecular Formula | C9H16N2O2 |
| Molecular Weight | 184.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Terazosin EP Impurity N (C9H16N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Terazosin EP Impurity N (CAS 63074-07-7, C9H16N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H16N2O2 |
| Molecular Weight | 184.24 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 2 |
Related Terazosin Standards
- Terazosin Hydrochloride Dihydrate EP Impurity N (CAS 412334-56-6)
- Terazosin Impurity 33 (CAS 2470438-57-2)
- Terazosin Impurity 4 (CAS 20197-86-8)
- Terazosin Impurity 18 (CAS CATO-C4X-134918)
- Terazosin EP Impurity M (CAS 31350-27-3)
- Terazosin EP Impurity O (CAS 547730-06-3)
- Terazosin Hydrochloride Dihydrate EP Impurity O (CAS CATO-C4X-134929)
- Terazosin RC 2 (CAS 113534-03-5)
Recommended Standards
- Buspirone Impurity 20 (CAS 1821194-01-7)
- Anastrozole Impurity 24 (CAS CATO-C4X-123924)
- Mesna EP Impurity A (CAS 25985-57-3)
- 1,5-Naphthyridine-3-carboxylic acid 90418-64-7 C9H6N2O2 V8914 (CAS 90418-64-7)
- Brexpiprazole Impurity 136 (CAS 2657666-89-0)
- Relebactam Impurity 18 (CAS CATO-C4X-214418)
- Iobitridol Impurity 15 (CAS CATO-C4X-317815)
- (R)-4-Nitrophenyl 2-aminopropanoate hydrochloride (CAS 81086-57-9)
- Resminostat hydrochloride, 98% (CAS 1187075-34-8)
- Phytomenadione/Vitamin K1 Impurity 111 (CAS CATO-C4X-2207111)
- tert-Butyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)allyl)carbamate (CAS 1374106-06-5)
- 3-(1-Aminobutan-2-yl)pyrrolidin-3-ol (CAS 1532609-26-9)
- 1-Ethyl-3-ethynyl-1H-pyrazole (CAS 1354706-83-4)
- Endo-38a-Pro-Exenatide trifluoroacetate salt (CAS 1678416-95-9)
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