Cabozantinib Impurity 26 CAS 6315-89-5
| CAS No. | 6315-89-5 |
| Molecular Formula | C8H11NO2 |
| Molecular Weight | 153.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cabozantinib Impurity 26.
CATO supplies Cabozantinib Impurity 26 (CAS 6315-89-5), a pharmacopoeial impurity reference standard (molecular formula C8H11NO2, MW 153.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Cabozantinib Impurity 26 (C8H11NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11NO2 |
| Molecular Weight | 153.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Cabozantinib Standards
- Cabozantinib Impurity G (CAS 26198-19-6)
- Cabozantinib Impurity 9 (CAS 3505-87-1)
- Cabozantinib Impurity 38 (CAS 352-15-8)
- Cabozantinib Impurity 20 (CAS CATO-C4X-201820)
- Cabozantinib Impurity 1 (CAS CATO-C4X-20181)
- Cabozantinib Impurity 10 (CAS 98300-41-5)
- Cabozantinib Impurity 42 (CAS 95262-10-5)
- Cabozantinib Impurity 12 (CAS 145591-80-6)
Recommended Standards
- Dopamine Impurity 65 (CAS CATO-C4X-190865)
- Carteolol Impurity 29 (CAS 23674-56-8)
- Dopamine (CAS 51-61-6)
- Perospirone Impurity 19 (CAS 117307-09-2)
- Deferasirox EP Impurity D (CAS 2254105-61-6)
- Alprazolam EP Impurity B (CAS CATO-C4X-146014)
- Avanafil Impurity 7 (CAS CATO-C4X-11187)
- 5,5-Dimethyl-2-phenyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one (CAS 109300-04-1)
- Furo[3,2-b]pyridin-2-ol (CAS 88011-99-8)
- 2-Hydroxy-4-n-octyloxybenzophenone (CAS 1843-05-6)
- (2E)-2-[(E)-Benzoyl]-3-[(quinolin-8-yl)amino]prop-2-enenitrile (CAS 1025150-25-7)
- Erlotinib Impurity 74 (CAS CATO-C4X-106974)
- N-C16-desoxymethylsphinganine (CAS 1246298-42-9)
- Semaglutide (CAS 910463-68-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com