2-Chloro-4-(thiophen-3-yl)pyrimidine CAS 63558-68-9
| CAS No. | 63558-68-9 |
| Molecular Formula | C8H5ClN2S |
| Molecular Weight | 196.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-4-(thiophen-3-yl)pyrimidine.
CATO supplies 2-Chloro-4-(thiophen-3-yl)pyrimidine (CAS 63558-68-9), a certified reference material (molecular formula C8H5ClN2S, MW 196.66 g/mol) for analytical method development and quality control.
Structurally, 2-Chloro-4-(thiophen-3-yl)pyrimidine (C8H5ClN2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 196.66 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2S |
| Molecular Weight | 196.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-4-(pyridin-4-yl)thiazole (CAS 103317-31-3)
- 4-Chloro-2-(thiophen-3-yl)pyrimidine (CAS 1156237-51-2)
- 2-Chloro-4-(pyridin-2-yl)thiazole (CAS 1188164-65-9)
- 2-Chloro-4-(pyridin-3-yl)thiazole (CAS 1188164-72-8)
- 4-Chloro-2-(thiophen-2-yl)pyrimidine (CAS 125904-07-6)
- 2-Chloro-5-phenyl-1,3,4-thiadiazole (CAS 13373-11-0)
- 4-chloro-1,2-dihydrophthalazine-1-thione (CAS 14062-52-3)
- 2-Chloro-6-(thiophen-2-yl)pyrazine (CAS 1484099-08-2)
Recommended Standards
- 2-Chloro-4-(thiophen-2-yl)pyrimidine (CAS 83726-75-4)
- 2-Chloro-5-(2-thienyl)pyrazine (CAS 912762-30-2)
- 2-(6-Chloropyridin-3-yl)thiazole (CAS 760193-03-1)
- 2-Chloro-6-(thiophen-3-yl)pyrazine (CAS 426829-59-6)
- 4-Amino-2,2-dimethyl-3-phenylbutan-1-ol (CAS 1423025-68-6)
- (11aR,11'aR)-6,6'-[[1,1'-Biphenyl]-2,2'-diylbis(oxy)]bis[4,8-bis(1,1-dimethylethyl)-1,2,10,11-tetramethyldibenzo[d,f][1,3,2]dioxaphosphepin (CAS 729572-46-7)
- 2-(2,6-Difluorophenyl)aniline (CAS 76838-89-6)
- 1-(Pyridin-3-yl)cyclopropanecarboxylic acid hydrobromide (CAS 1268444-68-3)
- 3,5-Dichloro-1-methyl-6-phenylpyrazin-2(1H)-one (CAS 1269533-57-4)
- 4-Bromo-6-methoxyquinoline-3-carboxylic acid (CAS 872714-51-7)
- (1R,4S)-4-Amino-3,3-difluorocyclopentane-1-carboxylic acid (CAS 1923827-00-2)
- 2-Chloro-1-Methylpyridinium Trifluoromethanesulphonate (CAS 84030-18-2)
- (S)-3-(2-methoxyphenoxy)pyrrolidine (CAS 788123-19-3)
- Semaglutide impurity 197 (CAS CATO-C4X-2226197)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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