2-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-oxo-N-[4-(trifluoromethyl)phenyl]acetamide CAS 866152-59-2
| CAS No. | 866152-59-2 |
| Molecular Formula | C21H16ClF3N2O2 |
| Molecular Weight | 420.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 420.81 g/mol gives 2-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-oxo-N-[4-(trifluoromethyl)phenyl]acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-oxo-N-[4-(trifluoromethyl)phenyl]acetamide (CAS 866152-59-2), molecular formula C21H16ClF3N2O2 and molecular weight 420.81 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-oxo-N-[4-(trifluoromethyl)phenyl]acetamide (C21H16ClF3N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 420.81 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-oxo-N-[4-(trifluoromethyl)phenyl]acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H16ClF3N2O2 |
| Molecular Weight | 420.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- N-[(4-Chlorophenyl)methyl]-2-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide (CAS 338782-35-7)
- 2-(4-Chlorophenyl)-N-((dimethylamino)methylene)-2-(3-(trifluoromethyl)quinoxalin-2-yl)acetamide (CAS 338412-27-4)
- 2-((5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-methoxy-4-nitrophenyl)acetamide (CAS 332160-29-9)
- 3-(4-((1-(4-Chlorophenyl)-3-methyl-1H-pyrazol-5-yl)methoxy)-3,5-difluorophenyl)-2-methylpropanoic acid (CAS 1224102-50-4)
- 2-(4-Chlorophenyl)-7-ethoxy-5-(4-nitrophenyl)-3H-benzo[e][1,2,4]triazepine (CAS 444159-02-8)
- (4-Chlorophenyl)(3-(1-((2-fluoro-[1,1'-biphenyl]-4-yl)oxy)ethyl)-1H-pyrazol-1-yl)methanone (CAS 477709-14-1)
- (5Z)-5-{[(2-chlorophenyl)amino]methylidene}-4-(4-fluorophenyl)-1-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrol-2-one (CAS 339096-93-4)
- (5Z)-5-{[(3-chlorophenyl)amino]methylidene}-4-(4-fluorophenyl)-1-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrol-2-one (CAS 339096-94-5)
Recommended Standards
- 3-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-benzoic acid 4-chloro-phenyl ester (CAS 1311280-37-1)
- 2-Chloro-5-nitro-N-(4-(quinoxalin-2-yloxy)phenyl)benzamide (CAS 647853-12-1)
- 4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-benzoic acid 4-chloro-phenyl ester (CAS 1311279-75-0)
- 3-[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenoxy)methyl]benzamide (CAS 339020-28-9)
- 4-Bromo-6-chloro-7-methyl-1H-indole (CAS 1082040-80-9)
- 4-{[1,1'-Biphenyl]-4-carbonyl}-8-ethyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326810-61-0)
- 3-(Aminomethyl)tetrahydropyran-3-ol (CAS 1342771-66-7)
- (R)-tert-Butyl 2-methylpyrrolidine-1-carboxylate (CAS 157007-54-0)
- 5-(6-Ethoxypyridazin-3-yl)-2-methylaniline (CAS 1286721-98-9)
- (S)-1-isopropylpiperidin-3-amine (CAS 1149384-35-9)
- N,N-Bis(ethylmethanethiosulfonate) Biotinamide (CAS 1217607-38-9)
- Antagonist G (CAS 115150-59-9)
- TTCOOEt-2Br (CAS 1800376-55-9)
- Tyr-Proinsulin C-Peptide (55-89) (human) (CAS 139532-11-9)
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