1-Bromo-4-((2,2,2-trifluoroethyl)sulfonyl)benzene CAS 648905-23-1

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Bromo-4-((2,2,2-trifluoroethyl)sulfonyl)benzene.

1-Bromo-4-((2,2,2-trifluoroethyl)sulfonyl)benzene (CAS 648905-23-1), molecular formula C8H6BrF3O2S and molecular weight 303.10 g/mol, is a CATO reference standard with documented purity and traceability.

1-Bromo-4-((2,2,2-trifluoroethyl)sulfonyl)benzene (C8H6BrF3O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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