Bis-trifluoroethyl Ethylphosphonate CAS 650-16-8
| CAS No. | 650-16-8 |
| Molecular Formula | C6H9F6O3P |
| Molecular Weight | 274.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Bis-trifluoroethyl Ethylphosphonate (CAS 650-16-8) is a high-purity analytical reference standard with the molecular formula C6H9F6O3P and a molecular weight of 274.10 g/mol.
Structurally, Bis-trifluoroethyl Ethylphosphonate (C6H9F6O3P) contains a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of -0.5, corresponding to approximately 0 ring(s) or double-bond equivalent(s). With a molecular weight of 274.10 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Bis-trifluoroethyl Ethylphosphonate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H9F6O3P |
| Molecular Weight | 274.10 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | -0.5 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Bis Standards
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- 2,2,2-Trifluoroethyl n-(5,6,7,8-tetrahydronaphthalen-1-yl)carbamate (CAS 1087798-08-0)
- Benzyl 1-(2,2,2-trifluoroethyl)azetidine-3-carboxylate (CAS 1803583-78-9)
- 2-(2,2,2-Trifluoroethyl)-4-((2,2,2-trifluoroethyl)amino)phenol (CAS 1309602-67-2)
- 2,2,2-trifluoroethyl N-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)carbamate (CAS 1482630-83-0)
- 2,2,2-trifluoroethyl 2,3,4-trifluorophenylcarbamate (CAS 1087788-69-9)
- Ethyl 3-(2,2,2-trifluoroethyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-7-carboxylate (CAS 1956322-85-2)
Recommended Standards
- 5-Iodo-2-(pyrrolidin-1-yl)pyridine (CAS 494771-62-9)
- Ethyl 5,7-dichloro-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 876391-25-2)
- 4-Iodo-1-phenylbutan-1-one (CAS 65488-05-3)
- Methyl 5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxylate (CAS 851785-48-3)
- (3E)-3-{[2-(4-benzylpiperazin-1-yl)-1,3-thiazol-5-yl]methylidene}-2,3-dihydro-1H-indol-2-one (CAS 882748-23-4)
- N-(4-amino-2-methoxyphenyl)-2-methylbenzamide (CAS 436089-19-9)
- 3-((3,5-Dimethyl-4-nitro-1h-pyrazol-1-yl)methyl)benzohydrazide (CAS 402768-47-2)
- 40737-92-6 Isocalolongic acid (CAS 40737-92-6)
- (R)-4-Methylhomophenylalanine (CAS 1089276-04-9)
- Torasemide Impurity 12 (CAS 99300-68-2)
- 6-(Dimethylamino)hexan-1-ol (CAS 1862-07-3)
- (5R)-(+)-2,2,3-Trimethyl-5-benzyl-4-imidazolidinone dichloroacetic acid (5R)-2,2,3-Trimethyl-5-phenylmethyl-4-imidazolidinone dichloroacetic acid 857303-87-8 (CAS 857303-87-8)
- Methyl 2,5-dimethyl-1H-indole-7-carboxylate (CAS 1427377-15-8)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
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