N1-(3-chloro-4-fluorophenyl)-3-{[3-(3-chloro-4-fluoroanilino)-3-oxopropyl]dithio}propanamide CAS 650592-32-8
| CAS No. | 650592-32-8 |
| Molecular Formula | C18H16Cl2F2N2O2S2 |
| Molecular Weight | 465.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N1-(3-chloro-4-fluorophenyl)-3-{[3-(3-chloro-4-fluoroanilino)-3-oxopropyl]dithio}propanamide.
N1-(3-chloro-4-fluorophenyl)-3-{[3-(3-chloro-4-fluoroanilino)-3-oxopropyl]dithio}propanamide (CAS 650592-32-8) is a high-purity analytical reference standard with the molecular formula C18H16Cl2F2N2O2S2 and a molecular weight of 465.36 g/mol.
N1-(3-chloro-4-fluorophenyl)-3-{[3-(3-chloro-4-fluoroanilino)-3-oxopropyl]dithio}propanamide (C18H16Cl2F2N2O2S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N1-(3-chloro-4-fluorophenyl)-3-{[3-(3-chloro-4-fluoroanilino)-3-oxopropyl]dithio}propanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16Cl2F2N2O2S2 |
| Molecular Weight | 465.36 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related N Standards
- N1-(3-chloro-2-fluorophenyl)-3-{[3-(3-chloro-2-fluoroanilino)-3-oxopropyl]dithio}propanamide (CAS 650592-34-0)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(phenyl)methyl)-4-(4-chlorophenyl)thiazole (CAS 339104-37-9)
- 1-(2-{6-[(2-chloro-6-fluorophenyl)methyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-yl}thiophen-3-yl)-2,5-dimethyl-1H-pyrrole (CAS 439111-87-2)
- Methyl 3-((4-(5-chloro-2-methylphenyl)piperazin-1-yl)sulfonyl)benzo[b]thiophene-2-carboxylate (CAS 899725-40-7)
- 9,9'-(5-Chloro-1,3-phenylene)diphenanthrene (CAS 1369431-34-4)
- N-(3-chloro-2-methylphenyl)-2-((5-(2-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 482650-60-2)
- Methyl 2-(2-(4-chloro-2-methylphenoxy)acetamido)-4-methyl-5-(piperidine-1-carbonyl)thiophene-3-carboxylate (CAS 335410-34-9)
- N-(3-((5-Chloro-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)acrylamide (CAS 1214265-56-1)
Recommended Standards
- Arbidol Impurity 23 (CAS CATO-C4X-112923)
- 2-{[2-(4-bromophenyl)-2-oxoethyl]sulfanyl}-3-(4-methylphenyl)-3,4-dihydroquinazolin-4-one (CAS 331972-22-6)
- 2-((5-(2-Bromophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-phenylacetamide (CAS 332388-13-3)
- Flupyrsulfuron-methyl (CAS 144740-53-4)
- 2-Amino-4-(trifluoromethyl)pyridine-3-acetonitrile (CAS 1228898-39-2)
- (3-Chloropropanesulfonyl)benzene (CAS 19432-96-3)
- Fmoc-5-amino-1,3-cyclohexadiene-1-carboxylic acid (CAS 1185294-86-3)
- (2-(sec-Butoxy)phenyl)methanamine (CAS 1042628-16-9)
- 1-(3-Chlorophenyl)-3-(p-tolyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-21-9)
- 2-(Bromomethyl)-6-(difluoromethyl)-4-iodo-3-nitropyridine (CAS 1806860-79-6)
- 3-Benzoyldihydrofuran-2(3H)-one (CAS 21034-21-9)
- 2-Chloro-N-(3,4-dimethylisoxazol-5-yl)acetamide (CAS 69000-38-0)
- 1,2:3,4-DI-o-isopropylidene-l-arabinopyranose (CAS 212069-31-3)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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