N1-(3-chloro-2-fluorophenyl)-3-{[3-(3-chloro-2-fluoroanilino)-3-oxopropyl]dithio}propanamide CAS 650592-34-0
| CAS No. | 650592-34-0 |
| Molecular Formula | C18H16Cl2F2N2O2S2 |
| Molecular Weight | 465.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies N1-(3-chloro-2-fluorophenyl)-3-{[3-(3-chloro-2-fluoroanilino)-3-oxopropyl]dithio}propanamide (CAS 650592-34-0), a certified reference material (molecular formula C18H16Cl2F2N2O2S2, MW 465.36 g/mol) for analytical method development and quality control.
Structurally, N1-(3-chloro-2-fluorophenyl)-3-{[3-(3-chloro-2-fluoroanilino)-3-oxopropyl]dithio}propanamide (C18H16Cl2F2N2O2S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 465.36 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H16Cl2F2N2O2S2 |
| Molecular Weight | 465.36 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related N Standards
- N1-(3-chloro-4-fluorophenyl)-3-{[3-(3-chloro-4-fluoroanilino)-3-oxopropyl]dithio}propanamide (CAS 650592-32-8)
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- Methyl 3-((4-(5-chloro-2-methylphenyl)piperazin-1-yl)sulfonyl)benzo[b]thiophene-2-carboxylate (CAS 899725-40-7)
- 9,9'-(5-Chloro-1,3-phenylene)diphenanthrene (CAS 1369431-34-4)
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- N-(3-((5-Chloro-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)acrylamide (CAS 1214265-56-1)
Recommended Standards
- 2-{[2-(4-bromophenyl)-2-oxoethyl]sulfanyl}-3-(4-methylphenyl)-3,4-dihydroquinazolin-4-one (CAS 331972-22-6)
- Flupyrsulfuron-methyl (CAS 144740-53-4)
- Arbidol Impurity 23 (CAS CATO-C4X-112923)
- N-(2,4-dichlorophenyl)-2-((4-methoxy-N-phenylphenyl)sulfonamido)acetamide (CAS 339013-29-5)
- Zolpidem tartrate Impurity 15 (CAS 51012-65-8)
- 5,5'-(Anthracene-9,10-diyl)bis(thiophene-2-carbaldehyde) (CAS 1355622-47-7)
- 1-Piperidinepropanoic acid, 4-(Ethoxycarbonyl)- (CAS 220676-64-2)
- N-(2-methoxybenzyl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide (CAS 866051-29-8)
- (R)-4-Ethoxy-2-(methylthio)-6-(pyrrolidin-3-yloxy)pyrimidine hydrochloride (CAS 1353995-17-1)
- 4-(Piperidin-1-ylmethyl)benzenethiol (CAS 1211508-32-5)
- 2-(Piperidin-4-yl)-1-propyl-1H-indole (CAS 1447949-82-7)
- 4,6-Dichloro-N-(4,4-dimethylcyclohexyl)-1H-indole-2-carboxamide (CAS 1473450-60-0)
- (3-(1,3-Dioxolan-2-yl)phenyl)(cyclobutyl)methanone (CAS 898759-74-5)
- Semaglutide Impurity 6 (CAS 62-57-7)
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