5-Phenyldihydropyrimidine-2,4(1H,3H)-dione CAS 652992-79-5
| CAS No. | 652992-79-5 |
| Molecular Formula | C10H10N2O2 |
| Molecular Weight | 190.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Phenyldihydropyrimidine-2,4(1H,3H)-dione.
CATO supplies 5-Phenyldihydropyrimidine-2,4(1H,3H)-dione (CAS 652992-79-5), a certified reference material (molecular formula C10H10N2O2, MW 190.20 g/mol) for analytical method development and quality control.
The molecular framework of 5-Phenyldihydropyrimidine-2,4(1H,3H)-dione (C10H10N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Phenyldihydropyrimidine-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10N2O2 |
| Molecular Weight | 190.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 2 |
Related Phenyldihydropyrimidine Standards
Recommended Standards
- 5-Oxo-5,6,7,8-tetrahydroquinoline-7-carboxamide (CAS 54318-91-1)
- 5-Propionyl-1H-benzo[d]imidazol-2(3H)-one (CAS 93202-42-7)
- 5-Oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid (CAS 3470-46-0)
- 6-(2-Cyanopropan-2-yl)picolinic acid (CAS 878744-16-2)
- 3-(1-Ethyl-1h-1,2,4-triazol-5-yl)propanoic acid (CAS 1250803-63-4)
- n-(3-Ethoxypropyl)bicyclo[2.2.1]heptan-2-amine (CAS 1247415-99-1)
- 1-(4-Bromophenyl)-2,3-butadien-1-one (CAS 378186-96-0)
- 2,4-Dimethyl-5-(2-methylbenzenesulfonyl)-6-(2-methylpropoxy)-3-phenylpyridine (CAS 338412-18-3)
- Avatrombopag Impurity 57 (CAS CATO-C4X-223457)
- 6-Bromo-1-(phenylsulfonyl)-1h-indole-3-carbaldehyde (CAS 1092460-47-3)
- Cloxacillin Impurity 28 (CAS 3717-27-9)
- (s)-3-Amino-3-(1-methyl-1h-imidazol-5-yl)propanoic acid (CAS 1568221-37-3)
- 3-Cyclopropoxy-6-ethylpicolinamide (CAS 1243361-91-2)
- Semaglutide impurity 29 (CAS CATO-C4X-222629)
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