Cloxacillin Impurity 28 CAS 3717-27-9
| CAS No. | 3717-27-9 |
| Molecular Formula | C7H6ClNO |
| Molecular Weight | 155.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Cloxacillin Impurity 28 (CAS 3717-27-9) is a certified pharmaceutical impurity reference standard with the molecular formula C7H6ClNO and a molecular weight of 155.58 g/mol.
Based on its molecular formula C7H6ClNO, Cloxacillin Impurity 28 contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 155.58 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Cloxacillin Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6ClNO |
| Molecular Weight | 155.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Cloxacillin Standards
- Cloxacillin Impurity 29 (CAS 1383929-39-2)
- Cloxacillin Impurity 16 (CAS 1143-82-4)
- Cloxacillin EP Impurity D (CAS 23598-72-3)
- Cloxacillin Impurity 23 (CAS CATO-C4X-159723)
- Cloxacillin Impurity 27 (CAS CATO-C4X-159727)
- Cloxacillin Impurity 26 (CAS CATO-C4X-159726)
- Cloxacillin Impurity N1 (CAS 4357-94-2)
- Cloxacillin Impurity 15 (CAS 1598387-74-6)
Recommended Standards
- Rebamipide impurity 19 (CAS 698-16-8)
- Dotinurad Impurity 145 (CAS 2596-93-2)
- Rebamipide Impurity 14 (CAS 619-56-7)
- 2-Chloroprop-2-ene-1-sulfonamide (CAS 1432682-13-7)
- Tadalafil Impurity 101 (CAS 20850-43-5)
- Mometasone Impurity 31 (CAS CATO-C4X-170431)
- Agomelatine Impurity 32 (CAS 138112-79-5)
- N-Desmethyl 3-Hydroxy Mepivacaine (CAS 247061-17-2)
- 2-(Furan-2-yl)-1H-imidazole (CAS 89795-49-3)
- 6-Benzylquinoline (CAS 54884-99-0)
- 3-Bromoheptan-4-one (CAS 42330-10-9)
- 3-(6-Iodo-1-oxoisoindolin-2-yl)piperidine-2,6-dione (CAS 2757572-60-2)
- 4,4’-Dibromotriphenylamine (CAS 81090-53-1)
- Semaglutide Impurity 143 (CAS CATO-C4X-2226143)
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