Rosuvastatin Impurity 216 CAS 65372-09-0
| CAS No. | 65372-09-0 |
| Molecular Formula | C10H14O3 |
| Molecular Weight | 182.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Rosuvastatin Impurity 216 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Rosuvastatin Impurity 216 (CAS 65372-09-0), a pharmacopoeial impurity reference standard (molecular formula C10H14O3, MW 182.22 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Rosuvastatin Impurity 216 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 182.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C10H14O3 |
| Molecular Weight | 182.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
Related Rosuvastatin Standards
- Rosuvastatin Impurity 253 (CAS 958358-67-3)
- Rosuvastatin Impurity 252 (CAS 587855-03-6)
- Rosuvastatin Impurity 197 (CAS 727382-14-1)
- Rosuvastatin Impurity 198 (CAS 5292-43-3)
- Rosuvastatin Impurity 32 (CAS 123185-88-6)
- Rosuvastatin Impurity 33 (CAS CATO-C4X-116933)
- Rosuvastatin Impurity 9 (CAS CATO-C4X-11699)
- Rosuvastatin Impurity 90 (CAS 934-34-9)
Recommended Standards
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- Cefotaxime Impurity 21 (CAS CATO-C4X-120121)
- Sugammadex Impurity(M-1)S-Z3 (CAS CATO-CPS-2404001)
- Drotaverin Impurity 64 (CAS CATO-C4X-243564)
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- 5-(4-Bromophenyl)-6-methylthiazolo[3,2-b][1,2,4]triazole (CAS 1574587-82-8)
- 4-(2-Methyl-1,3-thiazol-4-yl)benzoic acid (CAS 294620-60-3)
- (E)-3-(benzo[d][1,3]dioxol-5-yl)-N-(4-cyclohexylphenyl)acrylamide (CAS 329777-41-5)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com