Deferasirox Impurity N16 CAS 6543-57-3
| CAS No. | 6543-57-3 |
| Molecular Formula | C28H16O8 |
| Molecular Weight | 480.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Deferasirox Impurity N16 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Deferasirox Impurity N16 (CAS 6543-57-3, C28H16O8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Deferasirox Impurity N16 (C28H16O8) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H16O8 |
| Molecular Weight | 480.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Deferasirox Standards
- Deferasirox Impurity 10 (CAS 1395346-28-7)
- Deferasirox Impurity 18 (CAS 1395346-29-8)
- Deferasirox acyl-β-D-glucuronide (CAS 1233196-91-2)
- Deferasirox 2-Glucuronide (CAS 1233196-92-3)
- Deferasirox EP Impurity E (CAS 201530-79-2)
- Deferasirox Impurity N2 (CAS 524746-12-1)
- Deferasirox Impurity 14 (CAS 524746-13-2)
- Deferasirox Impurity 9 (CAS 1266741-05-2)
Recommended Standards
- 2,3-Dehydrosilybin A (CAS 25166-14-7)
- Bis-t-23 (CAS 171674-76-3)
- 2,3-Dehydrosilychristin (CAS 57499-41-9)
- 2-(4-{[3,5-bis(trifluoromethyl)phenyl]methoxy}phenyl)-4-(thiophen-2-yl)pyrimidine (CAS 477862-24-1)
- Mycophenolate Mofetil Impurity 14 (CAS 33431-38-8)
- Esmolol Impurity 59 (CAS 22367-76-6)
- Ondansetron EP Impurity A (CAS 119812-29-2)
- 2-Bromo-1-(3-bromopropyl)-4-fluorobenzene (CAS 1057678-47-3)
- 2-Oxo-2-phenylethyl 4-fluorobenzoate (CAS 55153-22-5)
- 4-(pyridin-2-yl)-2,3-dihydro-1,3-thiazol-2-one (CAS 805983-92-0)
- 16-Bromohexadec-1-ene (CAS 118625-56-2)
- 2-(3-amino-1H-1,2,4-triazol-1-yl)acetic acid dihydrochloride (CAS 1909319-29-4)
- 4-Bromooxazolo[4,5-c]pyridine (CAS 1936080-23-7)
- Semaglutide impurity 258 (CAS CATO-C4X-2226258)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com