Doxycycline EP Impurity C CAS 6543-77-7
| CAS No. | 6543-77-7 |
| Molecular Formula | C22H24N2O8 |
| Molecular Weight | 444.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 444.43 g/mol gives Doxycycline EP Impurity C distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Doxycycline EP Impurity C (CAS 6543-77-7) is a certified pharmaceutical impurity reference standard with the molecular formula C22H24N2O8 and a molecular weight of 444.43 g/mol.
The molecular framework of Doxycycline EP Impurity C (C22H24N2O8) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Doxycycline EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H24N2O8 |
| Molecular Weight | 444.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Doxycycline Standards
- Doxycycline EP Impurity A (CAS 3219-99-6)
- Doxycycline EP Impurity D (CAS 97583-08-9)
- Doxycycline Impurity 8 (CAS CATO-C4X-19318)
- Doxycycline (CAS 564-25-0)
- Doxycycline Impurity 21 (CAS CATO-C4X-193121)
- Doxycycline EP Impurity F (CAS 122861-53-4)
- Doxycycline EP Impurity B (CAS CATO-C4X-19312)
- Doxycycline-d3 (CAS 2747918-45-0)
Recommended Standards
- Thalidomide-O-PEG3-propargyl (CAS 2098799-76-7)
- N-(3-cyano-4-((3-(trifluoromethyl)phenyl)sulfinyl)phenyl)-3-methoxybenzamide (CAS 477710-04-6)
- Oxytetracycline EP Impurity B (CAS 60-54-8)
- Methyl 4-O-[4-6-O-benzylidene)-β-D-galactopyranosyl] β-D-glucopyranoside (CAS 56865-31-7)
- Piracetam impurity 25 (CAS CATO-C4X-123525)
- Carbocisteine Impurity 19 (CAS 14226-97-2)
- Loratadine Impurity 74 (CAS 31255-58-0)
- Benzyl 6-(benzylcarbamoyl)-4-(trifluoromethyl)pyridine-2-carboxylate (CAS 1211775-60-8)
- 2-Amino-5-bromonicotinaldehyde hydrobromide (CAS 709650-48-6)
- 4-Amino-2-methylquinolin-3-ol (CAS 61358-60-9)
- (4-Methoxyphenyl)(6-(4-methoxyphenyl)pyridin-3-yl)methanone (CAS 53670-04-5)
- 4-Methyl-2-pyrrolidin-1-yl-thiazole-5-carboxylic acid (CAS 947013-57-2)
- N-propyl-N-(2-(2,4,6-trichlorophenoxy)ethyl)picolinamide (CAS 91406-37-0)
- Palmitoyl Pentapeptide-4 (CAS 214047-00-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com