Sitagliptin Phosphate CAS 654671-78-0
| CAS No. | 654671-78-0 |
| Molecular Formula | C16H15F6N5O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Sitagliptin Phosphate.
CATO supplies Sitagliptin Phosphate (CAS 654671-78-0), a certified reference material (molecular formula C16H15F6N5OH3O4P, MW 505.31 g/mol) for analytical method development and quality control.
Structurally, Sitagliptin Phosphate (C16H15F6N5OH3O4P) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.5, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 505.31 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H15F6N5O H3O4P |
| Molecular Weight | 505.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Sitagliptin Standards
- Sitagliptin Impurity 17 (CAS 1036273-20-7)
- Sitagliptin Impurity 966 (CAS 1151240-88-8)
- Sitagliptin Impurity 14 (CAS 1151240-91-3)
- Sitagliptin Impurity 12 HCl (CAS 1151240-91-3（free base）)
- Sitagliptin Impurity 77 (CAS 1152439-73-0)
- Sitagliptin Impurity 97 (CAS 1169707-29-2)
- Sitagliptin Tablets EP Impurity FP-E HCl (CAS 1204818-19-8)
- Sitagliptin Impurity 15 (CAS 1217809-78-3)
Recommended Standards
- (4-Hexylphenyl)methanamine (CAS 376640-08-3)
- 2-(2-oxo-2-phenylethoxy)-5-(trifluoromethyl)pyridinium-1-olate (CAS 263385-04-2)
- 2-(Difluoromethoxy)-3'-(trifluoromethoxy)-3-(trifluoromethyl)biphenyl (CAS 1261881-75-7)
- 1-Chloro-4-((prop-2-yn-1-yloxy)methyl)benzene (CAS 4039-86-5)
- 2-Methyl-3,3-diphenylpropanal (CAS 93433-63-7)
- 5-Propylpyrrolidin-2-one (CAS 17771-41-4)
- 2-Bromo-4-fluorobenzohydrazide (CAS 935657-73-1)
- 3-(1H-Pyrazolo[3,4-b]pyridin-3-yl)propanoic acid (CAS 1246520-77-3)
- 5-Bromo-2-(pyridin-2-ylmethoxy)benzaldehyde (CAS 892873-55-1)
- Pancreatic Polypeptide (1-17)-(Ala31,Aib32)-Neuropeptide Y (18-36) (human) trifluoroacetate salt (CAS 313988-70-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com