2,2,5-Trifluoro-1,3-benzodioxole CAS 656-43-9
| CAS No. | 656-43-9 |
| Molecular Formula | C7H3F3O2 |
| Molecular Weight | 176.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 176.09 g/mol gives 2,2,5-Trifluoro-1,3-benzodioxole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2,2,5-Trifluoro-1,3-benzodioxole (CAS 656-43-9), a certified reference material (molecular formula C7H3F3O2, MW 176.09 g/mol) for analytical method development and quality control.
2,2,5-Trifluoro-1,3-benzodioxole (C7H3F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H3F3O2 |
| Molecular Weight | 176.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Trifluoro Standards
- 2,4,6-Trifluoro-3-hydroxybenzaldehyde (CAS 1093253-75-8)
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- 2,3,5-Trifluoro-4-hydroxybenzaldehyde (CAS 676500-50-8)
- 2,2,2-Trifluoro-1-(pyrazin-2-yl)ethanone (CAS 1147103-48-7)
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Recommended Standards
- 2-(trifluoromethyl)cyclohexa-2,5-diene-1,4-dione (CAS 393-40-8)
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- 2,3,5-Trifluorobenzoic Acid (CAS 654-87-5)
- (4-Fluorophenyl)phosphonic acid (CAS 349-87-1)
- 1-((1,3,5-Trimethyl-1H-pyrazol-4-yl)sulfonyl)pyrrolidin-3-amine hydrochloride (CAS 1830788-91-4)
- 1,3-Dihydroxy-7,8,9,10-tetrahydro-6H-benzo[c]-chromen-6-one (CAS 3722-45-0)
- calciumdi-beta-alaninate (CAS 36321-40-1)
- 2-Methyl-2,3-dihydrobenzofuran-7-sulfonamide (CAS 89819-23-8)
- 4-Methoxy-5-methyl-2-oxazolecarboxylic Acid (CAS 143033-58-3)
- 1',3'-Dimethyl-7',9'-dihydrospiro[indoline-3,8'-purine]-2,2',6'(1'H,3'H)-trione (CAS 21943-52-2)
- 3-Amino-N-benzyl-N-propylpropanamide (CAS 1153538-23-8)
- 1-Methyl-4-oxopiperidine 1-oxide (CAS 223741-97-7)
- Methyl 3-[(cyclohexylamino)sulfonyl]thiophene-2-carboxylate (CAS 946742-04-7)
- endo-Gly31-Semaglutide (CAS CATO-C4X-2226282)
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