Cefotaxime EP Impurity D Sodium Salt CAS 65715-12-0
| CAS No. | 65715-12-0 |
| Molecular Formula | C16H16N5NaO7S2 |
| Molecular Weight | 477.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cefotaxime EP Impurity D Sodium Salt.
As a process- or degradation-related impurity, Cefotaxime EP Impurity D Sodium Salt (CAS 65715-12-0, C16H16N5NaO7S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Cefotaxime EP Impurity D Sodium Salt (C16H16N5NaO7S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.5, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 477.45 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cefotaxime EP Impurity D Sodium Salt meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16N5NaO7S2 |
| Molecular Weight | 477.45 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Cefotaxime Standards
- Cefotaxime Bromoacetyl analog (CAS 83305-12-8)
- Cefotaxime Impurity 16 (CAS CATO-C4X-120116)
- Cefotaxime Impurity 5 (CAS 64485-89-8)
- E-Cefotaxime S-Oxide (CAS 69132-42-9)
- Cefotaxime S-Oxide (CAS 97466-27-8)
- (E)-Cefotaxime S-Oxide (CAS CATO-C4X-120131)
- Cefotaxime S-Oxide (CAS CATO-C4X-120158)
- Cefotaxime S-Oxide 2 (CAS 71048-88-9)
Recommended Standards
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