Azacitidine Impurity 27 CAS 65886-71-7
| CAS No. | 65886-71-7 |
| Molecular Formula | C8H12N4O5 |
| Molecular Weight | 244.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Azacitidine Impurity 27 (CAS 65886-71-7), a pharmacopoeial impurity reference standard (molecular formula C8H12N4O5, MW 244.20 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C8H12N4O5, Azacitidine Impurity 27 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 244.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H12N4O5 |
| Molecular Weight | 244.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 4 |
Related Azacitidine Standards
- Azacitidine Impurity 14 (CAS 206269-46-7)
- Azacitidine (CAS 320-67-2)
- Azacitidine Impurity 3 (CAS 157771-77-2)
- Azacitidine Impurity 45 (CAS CATO-C4X-138845)
- Azacitidine Impurity 28 (CAS 3530-56-1)
- Azacitidine Impurity 29 (CAS 26524-60-7)
- Azacitidine Impurity 43 (CAS 13913-16-1)
- Azacitidine Impurity 52 (CAS 77172-20-4)
Recommended Standards
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- CAS 16535-78-7 (CAS 16535-78-7)
- Dexmedetomidine Impurity 8 (CAS CATO-C4X-12308)
- Fosfomycin Impurity 24 (CAS 1416734-33-2)
- Levosimendan Impurity 27 (CAS CATO-C4X-130827)
- (5Z,8Z,11Z,14Z)-N-(3-hydroxyphenyl)icosa-5,8,11,14-tetraenamide (CAS 183718-75-4)
- (2e)-3-(3-Fluoro-4-methoxyphenyl)prop-2-enoic acid (CAS 147906-08-9)
- 2-((5-Benzyl-1,3,4-oxadiazol-2-yl)thio)-N-(4-fluorophenyl)acetamide (CAS 332907-16-1)
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- Sodium Valproate Impurity 19 (CAS 616-62-6)
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Why CATO?
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