Methenamine Impurity 1 CAS 6623-56-9
| CAS No. | 6623-56-9 |
| Molecular Formula | C14H19N4O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 326.78 g/mol gives Methenamine Impurity 1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Methenamine Impurity 1 (CAS 6623-56-9), a pharmacopoeial impurity reference standard (molecular formula C14H19N4O3Cl, MW 326.78 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C14H19N4O3Cl, Methenamine Impurity 1 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 326.78 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Methenamine Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H19N4O3 Cl |
| Molecular Weight | 326.78 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Methenamine Standards
Recommended Standards
- Linaclotide Impurity 26 (CAS CATO-C4X-210626)
- Polidocanol Impurity 4 (Polidocanol E14) (CAS 54350-53-7)
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- Methyl 1-[(3,4-dichlorophenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxylate (CAS 338755-15-0)
- N-(2-Chloro-5-(trifluoromethyl)phenyl)pivalamide (CAS 13691-96-8)
- Roxadustat Glycine (CAS 808116-60-1)
- 2-Amino-5-ethylidene-1-methyl-1H-imidazol-4(5H)-one (CAS 119290-24-3)
- Flurbiprofen Impurity 128 (CAS 1515948-47-6)
- Spiro[2.2]pentan-1-ol (CAS 68423-22-3)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
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