3-Amino-N-(4-methoxybenzyl)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide CAS 664999-34-2
| CAS No. | 664999-34-2 |
| Molecular Formula | C22H22F3N3O2S |
| Molecular Weight | 449.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 449.49 g/mol gives 3-Amino-N-(4-methoxybenzyl)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Amino-N-(4-methoxybenzyl)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 664999-34-2), a certified reference material (molecular formula C22H22F3N3O2S, MW 449.49 g/mol) for analytical method development and quality control.
The molecular framework of 3-Amino-N-(4-methoxybenzyl)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (C22H22F3N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Amino-N-(4-methoxybenzyl)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H22F3N3O2S |
| Molecular Weight | 449.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 4-(5-amino-6-(1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl)pyrazin-2-yl)-N-cyclopropyl-N-methylbenzenesulfonamide (CAS 1396771-17-7)
- 3-Amino-4-phenyl-N-(o-tolyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 332114-37-1)
- 3-Amino-N-(2,6-dimethylphenyl)-4,6-diphenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332040-35-4)
- 3-Amino-N-(2-ethylphenyl)-4,6-diphenylthieno[2,3-b]pyridine-2-carboxamide (CAS 337495-86-0)
- 3-Amino-N-(3,4-dimethylphenyl)-4,6-diphenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332040-37-6)
- (R)-2-(1-Amino-2-(2,5-dibromophenyl)ethyl)-5-bromophenol, 97% (CAS 1585969-24-9)
- 3-Amino-N-(4-chloro-3-(trifluoromethyl)phenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 496019-30-8)
- Ethyl 2-amino-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(3-chlorothiophen-2-yl)-1H-pyrrole-3-carboxylate (CAS 341966-09-4)
Recommended Standards
- 2-{[3-cyano-6-ethyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinolin-2-yl]sulfanyl}-N-(3-methoxyphenyl)acetamide (CAS 664999-29-5)
- Mal-PEG8-alcohol (CAS 2353409-63-7)
- 2-{[3-cyano-4-(trifluoromethyl)-5H,6H,7H,8H,9H-cyclohepta[b]pyridin-2-yl]sulfanyl}-N-[(4-methoxyphenyl)methyl]acetamide (CAS 626227-51-8)
- Mycophenolate Mofetil EP Impurity G (CAS 224052-51-1)
- 2,2-Difluoro-2-(3-(trifluoromethyl)phenoxy)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 338792-03-3)
- Ethyl 11H-perfluoroundecanoate (CAS 1649-56-5)
- 4-Chloro-5,6-dihydrobenzo[h]quinazoline (CAS 57711-36-1)
- (R)-1-(2-Bromopyridin-3-yl)ethan-1-ol (CAS 2227862-24-8)
- Methyl 4-methoxy-2-methyl-5-(methylsulfonyl)benzoate (CAS 190367-90-9)
- (E)-3-(chloromethyl)-4-(2-ethoxybenzylidene)isoxazol-5(4H)-one (CAS 1142199-18-5)
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- 2-(3-Ethyl-1-methyl-1h-1,2,4-triazol-5-yl)aniline (CAS 1344234-55-4)
- (S)-3-(1-amino-2-methylpropyl)aniline (CAS 1213568-86-5)
- KALA Amphipathic Peptide (CAS 187987-64-0)
Why CATO?
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