Etomidate Impurity 7 CAS 66514-85-0
| CAS No. | 66514-85-0 |
| Molecular Formula | C13H17NO3 |
| Molecular Weight | 235.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Etomidate Impurity 7 (CAS 66514-85-0) is a certified pharmaceutical impurity reference standard with the molecular formula C13H17NO3 and a molecular weight of 235.28 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Etomidate Impurity 7 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 235.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H17NO3 |
| Molecular Weight | 235.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 1 |
Related Etomidate Standards
- Etomidate impurity 01 (CAS 66512-38-7)
- Etomidate Impurity 20 (CAS CATO-C4X-188420)
- Etomidate Impurity 27 (CAS CATO-C4X-188427)
- Etomidate impurity 60 (CAS CATO-C4X-188460)
- Etomidate Impurity 44 (CAS 39096-80-5)
- Etomidate Impurity 76 (CAS CATO-C4X-188476)
- （R)-Etomidate EP Impurity B (CAS 61045-91-8)
- S-(-)-Etomidate (CAS 56649-47-9)
Recommended Standards
- Prilocaine impurity 46 (CAS CATO-C4X-193446)
- Tenofovir alafenamide impurity 82 (CAS 126771-32-2)
- Prilocaine impurity 47 (CAS CATO-C4X-193447)
- Tenofovir alafenamide impurity 80 (CAS 126771-36-6)
- Esmolol Impurity 41 (CAS CATO-C4X-189141)
- Chlortetracycline Hydrochloride EP Impurity K (CAS CATO-C4X-233021)
- Desmopressin Tyrosine Oxidation Impurity 2 (CAS CATO-C4X-221519)
- Quinoline Impurity 23 (CAS 423126-64-1)
- 2-Chloro-N-(4-(pyrrolidin-1-yl)phenyl)acetamide (CAS 251097-15-1)
- tert-Butyl 3-(1-ethoxy-1-oxopropan-2-ylidene)azetidine-1-carboxylate (CAS 1692781-91-1)
- 7-PYridin-3-yl-2,3,4,5-tetrahydro-1,4-benzoxazepine dihydrochloride (CAS 2109576-41-0)
- Methyl 1-(1-benzylpiperidin-4-yl)-5-oxopyrrolidine-3-carboxylate (CAS 937601-54-2)
- tert-Butyl 4-(benzo[d]thiazol-2-yl)piperidine-1-carboxylate (CAS 1373879-28-7)
- Peptide YY (13-36) (canine, mouse, porcine, rat) (CAS 86895-09-2)
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