Cefadroxil Monohydrate CAS 66592-87-8
| CAS No. | 66592-87-8 |
| Molecular Formula | C16H17N3O5S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Cefadroxil Monohydrate (CAS 66592-87-8) is a high-purity analytical reference standard with the molecular formula C16H17N3O5SH2O and a molecular weight of 381.40 g/mol.
The molecular framework of Cefadroxil Monohydrate (C16H17N3O5SH2O) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Cefadroxil Monohydrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H17N3O5S H2O |
| Molecular Weight | 381.40 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cefadroxil Standards
- Cefadroxil EP Impurity D (CAS 144790-28-3)
- Cefadroxil USP Related Compound I (CAS 147103-94-4)
- Cefadroxil EP Impurity F (D-isomer) (CAS 147103-95-5)
- Cefadroxil Sulfoxide(RS) (CAS 182290-77-3)
- Cefadroxil Ethyl Homolog (CAS 2243976-70-5)
- Cefadroxil EP Impurity A(Amoxicillin EP Impurity I) (CAS 22818-40-2)
- Cefadroxil Impurity 3 (CAS 2378158-44-0)
- Cefadroxil Impurity 10 (CAS 2378158-45-1)
Recommended Standards
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- 2,3-Dibromo-4-(difluoromethoxy)benzaldehyde (CAS 1803812-87-4)
- (E)-Ethyl 4,4,4-trifluoro-3-methylbut-2-enoate (CAS 691-77-0)
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- 1-(4-(Aminomethyl)benzyl)piperidin-3-ol hydrochloride (CAS 1361114-17-1)
- (2-Isopropylpyridin-3-yl)methanamine (CAS 1546394-35-7)
- Methyl 2-(4-oxo-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-3(4h)-yl)acetate (CAS 450376-42-8)
- (3-(Trifluoromethyl)phenyl)zinc bromide, 0.50 M in THF (CAS 199465-55-9)
- Semaglutide Main Chain P29 (CAS 1169630-82-3)
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