5-chloro-[1,2,4]triazolo[4,3-a]pyridin-3-amine CAS 66999-63-1
| CAS No. | 66999-63-1 |
| Molecular Formula | C6H13ClN4 |
| Molecular Weight | 176.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-chloro-[1,2,4]triazolo[4,3-a]pyridin-3-amine is closely related to a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-chloro-[1,2,4]triazolo[4,3-a]pyridin-3-amine (CAS 66999-63-1) is a high-purity analytical reference standard with the molecular formula C6H13ClN4 and a molecular weight of 176.65 g/mol.
5-chloro-[1,2,4]triazolo[4,3-a]pyridin-3-amine (C6H13ClN4) contains a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H13ClN4 |
| Molecular Weight | 176.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
- 5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 1080467-50-0)
- 7-chloro-3-methyl-[1,2,4]triazolo[4,3-c]pyrimidine (CAS 1094292-91-7)
- 6-chloro-1H-pyrazolo[4,3-c]pyridin-3-amine (CAS 1206979-75-0)
- 5-chloro-3-methyl-2H-pyrazolo[4,3-d]pyrimidine (CAS 1208863-75-5)
- 5-chloro-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS 1245643-75-7)
- 5-chloro-1H-pyrazolo[4,3-b]pyridin-3-amine (CAS 1268522-21-9)
- 5-chloro-3-methyl-triazolo[4,5-b]pyridine (CAS 1353777-54-4)
- 7-chloro-5-methyl-[1,2,4]triazolo[4,3-c]pyrimidine (CAS 1354951-50-0)
Recommended Standards
- 4-chloropyrrolo[2,1-f][1,2,4]triazin-6-amine (CAS 2168463-27-0)
- 6-chloro-1H-imidazo[4,5-c]pyridin-4-amine (CAS 52559-17-8)
- 4-chloropteridine (CAS 72700-48-2)
- 6-chloropyrrolo[2,1-f][1,2,4]triazin-4-amine (CAS 939807-80-4)
- 5-Amino-N-(2,2-difluoroethyl)-4-fluoro-2-methylbenzamide (CAS 1877578-00-1)
- 2-(Benzo[d]isoxazol-3-yl)-N-(furan-2-ylmethyl)acetamide (CAS 950333-77-4)
- Glycidyl Methacrylate (stabilized with MEHQ) (CAS 106-91-2)
- (R)-1-(4-Chlorophenyl)ethanamine hydrochloride (CAS 1167414-87-0)
- 2,2,2-trifluoro-N-(2,2,2-trifluoroethyl)acetamide (CAS 407-37-4)
- 3-(4-Ethoxy-2-methylphenyl)isoxazol-5-amine (CAS 501325-98-0)
- 2-((4-(Tert-butyl)cyclohexyl)amino)propan-1-ol (CAS 1153893-60-7)
- 2-borono-1H-indole-1,6-dicarboxylic acid-1-(1,1-dimethylethyl) 6-methyl ester (CAS 848357-46-0)
- 2-(1-Methyl-1H-imidazol-5-yl)-6-oxo-1-propylpiperidine-3-carboxylic acid (CAS 1484814-49-4)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com