3-Bromo-5-chloro-[1,2,4]triazolo[4,3-a]pyridine CAS 66999-64-2
| CAS No. | 66999-64-2 |
| Molecular Formula | C6H3BrClN3 |
| Molecular Weight | 232.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Bromo-5-chloro-[1,2,4]triazolo[4,3-a]pyridine (C6H3BrClN3) is characterized by a nitrile group, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-Bromo-5-chloro-[1,2,4]triazolo[4,3-a]pyridine (CAS 66999-64-2) is a high-purity analytical reference standard with the molecular formula C6H3BrClN3 and a molecular weight of 232.47 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Bromo-5-chloro-[1,2,4]triazolo[4,3-a]pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H3BrClN3 |
| Molecular Weight | 232.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
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Recommended Standards
- 2-Bromo-8-chloroimidazo[1,2-b]pyridazine (CAS 2801720-19-2)
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- 2-Bromo-6-chloroimidazo[1,2-b]pyridazine (CAS 944902-75-4)
- 3-Bromo-6-chloroimidazo[1,2-a]pyrimidine (CAS 944906-48-3)
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- Insulin Degludec Impurity 7 (CAS CATO-C4X-21577)
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