N,N'-(1,2-Phenylene)dipicolinamide CAS 67455-94-1
| CAS No. | 67455-94-1 |
| Molecular Formula | C18H14N4O2 |
| Molecular Weight | 318.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N,N'-(1,2-Phenylene)dipicolinamide.
N,N'-(1,2-Phenylene)dipicolinamide (CAS 67455-94-1), molecular formula C18H14N4O2 and molecular weight 318.33 g/mol, is a CATO reference standard with documented purity and traceability.
N,N'-(1,2-Phenylene)dipicolinamide (C18H14N4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N,N'-(1,2-Phenylene)dipicolinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14N4O2 |
| Molecular Weight | 318.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 4 |
Recommended Standards
- N,N'-(1,2-phenylene)dinicotinamide (CAS 39642-80-3)
- N,N′-Bis-(4-pyridylformamide)-1,4-benzenediamine (CAS 55119-42-1)
- N,N'-(1,2-phenylene)diisonicotinamide (CAS 548480-36-0)
- N1,N4-Di(pyridin-4-yl)terephthalamide (CAS 216079-39-9)
- 1-(Tert-butoxycarbonyl)-3-(2-fluorophenyl)piperidine-3-carboxylic acid (CAS 2490698-38-7)
- 4-Bromo-1-(thiophen-3-ylmethyl)-1H-pyrazole (CAS 1179298-72-6)
- 3-Chloro-N-cyclopropylbenzenesulfonamide (CAS 1341378-31-1)
- (3,5-Dichlorophenyl)(thiophen-2-yl)methanol (CAS 1250544-03-6)
- Z-His-p-nitro-Phe-Phe-OMe (C-1990.0250) (CAS 15574-28-4)
- 5-(2,6-Difluorophenyl)nicotinic acid (CAS 1261998-47-3)
- Duloxetine Hydrochloride (CAS 136434-34-9)
- 4-(2-Chlorobenzyl)piperidine (CAS 251107-32-1)
- 4-Chloro-5-ethylthiophene-2-carbohydrazide (CAS 1399657-40-9)
- Semaglutide impurity 60 (CAS CATO-C4X-222660)
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