Valsartan impurity 5 CAS 676129-92-3
| CAS No. | 676129-92-3 |
| Molecular Formula | C19H21N5O2 |
| Molecular Weight | 351.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Valsartan impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Valsartan impurity 5 (CAS 676129-92-3) is a certified pharmaceutical impurity reference standard with the molecular formula C19H21N5O2 and a molecular weight of 351.40 g/mol.
Structurally, Valsartan impurity 5 (C19H21N5O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 351.40 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C19H21N5O2 |
| Molecular Weight | 351.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 5 |
Related Valsartan Standards
- Valsartan Impurity 103 (CAS 1391068-02-2)
- Valsartan Impurity 128 (CAS CATO-C4X-1057128)
- Valsartan Impurity 30 (CAS 209911-63-7)
- Valsartan Impurity 127 (CAS CATO-C4X-1057127)
- Valsartan Impurity 37 (CAS CATO-C4X-105737)
- Valsartan Impurity 62 (CAS 1314799-75-1)
- Valsartan Impurity 20 (CAS CATO-C4X-105720)
- Valsartan Impurity 109 (CAS 2407652-86-0)
Recommended Standards
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- Dabigatran Impurity 22 (CAS 1408238-41-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com