Valsartan Impurity 20 CAS CATO-C4X-105720
| CAS No. | CATO-C4X-105720 |
| Molecular Formula | C18H19N5O2 |
| Molecular Weight | 337.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Valsartan Impurity 20.
As a process- or degradation-related impurity, Valsartan Impurity 20 (CAS CATO-C4X-105720, C18H19N5O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Valsartan Impurity 20 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 337.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19N5O2 |
| Molecular Weight | 337.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Valsartan Standards
- Valsartan Impurity 109 (CAS 2407652-86-0)
- Valsartan Impurity 100 (CAS CATO-C4X-1057100)
- Valsartan impurity 7 (CAS 914465-68-2)
- Valsartan Impurity 37 (CAS CATO-C4X-105737)
- Valsartan Impurity 87 (CAS 196707-31-0)
- Valsartan Impurity 127 (CAS CATO-C4X-1057127)
- Valsartan Impurity 30 (CAS 209911-63-7)
- Valsartan Impurity 103 (CAS 1391068-02-2)
Recommended Standards
- N-Desmethyl pirenzepine (CAS 63257-31-8)
- Aficamten (CAS 2364554-48-1)
- N-(4-Methoxyphenyl)-3-(3-methylphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-95-9)
- Aficamten Impurity 2 (CAS CATO-C4X-34802)
- Famotidine Impurity 26 (CAS CATO-C4X-139226)
- Levofloxacin impurity 77 (CAS CATO-C4X-137177)
- Aficamten Impurity 5 (CAS CATO-C4X-34805)
- 5-Cyclopropyl-2-isopropylthiophen-3-amine hydrochloride (CAS 2567558-12-5)
- 2-Bromo-5-methoxypyridin-3-amine (CAS 1043688-99-8)
- 5-Chlorothiazole (CAS 4175-73-9)
- 3-(Cyclobutylmethoxy)-4-methylaniline (CAS 1485357-41-2)
- 4-Methylumbelliferyl 2,3,6-Tri-O-benzoyl-b-D-galactopyranoside (CAS 849207-61-0)
- Cefditoren-d3 (CAS 2747915-67-7)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
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