Valsartan Impurity 37 CAS CATO-C4X-105737
| CAS No. | CATO-C4X-105737 |
| Molecular Formula | C19H21ClN2O2 |
| Molecular Weight | 344.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Valsartan Impurity 37 (CAS CATO-C4X-105737), a pharmacopoeial impurity reference standard (molecular formula C19H21ClN2O2, MW 344.83 g/mol) used for the identification and quantification of trace impurities in APIs.
Valsartan Impurity 37 (C19H21ClN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Valsartan Impurity 37 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H21ClN2O2 |
| Molecular Weight | 344.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Valsartan Standards
- Valsartan Impurity 127 (CAS CATO-C4X-1057127)
- Valsartan Impurity 30 (CAS 209911-63-7)
- Valsartan Impurity 103 (CAS 1391068-02-2)
- Valsartan Impurity 128 (CAS CATO-C4X-1057128)
- Valsartan impurity 5 (CAS 676129-92-3)
- Valsartan Impurity 20 (CAS CATO-C4X-105720)
- Valsartan Impurity 109 (CAS 2407652-86-0)
- Valsartan Impurity 100 (CAS CATO-C4X-1057100)
Recommended Standards
- Methyl 4-(4-chlorophenyl)-4-oxo-2-[4-(propan-2-yl)phenyl]butanoate (CAS 199725-00-3)
- 2,4,6-Tribromoanisole (CAS 607-99-8)
- Fluorotris(triphenylphosphine)copper(I) (CAS 25753-74-6)
- 1-(4-(5-Chloro-2-methylphenyl)piperazin-1-yl)-2-phenoxyethan-1-one (CAS 1119391-88-6)
- Busulfan Impurity 21 (CAS CATO-C4X-145521)
- Biotin impurity 35 (CAS 1374019-64-3)
- Roxithromycin Impurity 18 (CAS 67796-27-4)
- 4-((3,5-Bis(trifluoromethyl)phenoxy)methyl)-5-(chloromethyl)-2-(4-(trifluoromethyl)phenyl)thiazole (CAS 1365033-43-7)
- 5-(1,3-Benzodioxol-5-yl)isoxazole-3-carboxylic acid (CAS 668971-47-9)
- 2-Deoxy-2-fluoro-D-glucose (CAS 29702-43-0)
- N-benzylquinoline-6-carboxamide (CAS 6843-60-3)
- 2-(Piperidin-1-yl)-1H-benzo[d]imidazole (CAS 2851-12-9)
- Methyl 2-(2-(cyanomethyl)phenyl)acetate (CAS 643021-02-7)
- Pheromone Biosynthesis Activating Neuropeptide (Helicoverpa assulta, Heliothis zea) (CAS 122071-54-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com