Camptothecin Impurity 9 CAS 67656-30-8
| CAS No. | 67656-30-8 |
| Molecular Formula | C20H16N2O5 |
| Molecular Weight | 364.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Camptothecin Impurity 9 (CAS 67656-30-8) is a certified pharmaceutical impurity reference standard with the molecular formula C20H16N2O5 and a molecular weight of 364.35 g/mol.
Camptothecin Impurity 9 (C20H16N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H16N2O5 |
| Molecular Weight | 364.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 2 |
Related Camptothecin Standards
- Camptothecin Impurity 10 (CAS 68426-53-9)
- Camptothecin impurity 17 (CAS 86639-48-7)
- 7-Methyl Camptothecin (CAS 78287-26-0)
- (R)-(-)-Camptothecin-d5 (CAS 1329793-44-3)
- (S)-(+)-Camptothecin D5 (CAS 1329616-37-6)
- Camptothecin Impurity 16 (CAS 870527-52-9)
- 11-Ethyl Camptothecin (CAS 185807-29-8)
- Camptothecin Impurity 12 (CAS 19685-10-0)
Recommended Standards
- Serotonin Impurity 11 (CAS CATO-C4X-253411)
- Serotonin Impurity 13 (CAS 55747-60-9)
- Irinotecan Hydrochloride Trihydrate EP Impurity B (CAS 19685-09-7)
- Ensifentrine impurity 23 (CAS 43113-25-3)
- Topiramate Impurity 9 (CAS 58238-46-3)
- Pramipexole Impurity 44 (CAS 1001648-65-2)
- Meropenem EP Impurity B2 (CAS CATO-C4X-130921)
- 2,2,2-Trifluoroethyl n-[3-(5-methyl-1h-pyrazol-4-yl)propyl]carbamate hydrochloride (CAS 1397062-20-2)
- 8-Methyl-3-methylene-8-azabicyclo[3.2.1]octane (CAS 99838-33-2)
- 2-(5,6-Dibromo-3-(difluoromethyl)pyridin-2-yl)acetonitrile (CAS 1806787-02-9)
- (R)-2-amino-3-(4-(2-fluoroethoxy)phenyl)propanoic acid (CAS 223463-90-9)
- 4-Chloro-3-(2-chloroethyl)-2-methyl-8-phenoxyquinoline (CAS 866133-53-1)
- 1-Methyl-3-phenylpiperidine (CAS 19509-11-6)
- Neuroendocrine Regulatory Peptide-1 (rat) (CAS 954420-51-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com