Camptothecin impurity 17 CAS 86639-48-7
| CAS No. | 86639-48-7 |
| Molecular Formula | C20H16N2O5 |
| Molecular Weight | 364.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Camptothecin impurity 17 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Camptothecin impurity 17 (CAS 86639-48-7, C20H16N2O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Camptothecin impurity 17 (C20H16N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Camptothecin impurity 17 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H16N2O5 |
| Molecular Weight | 364.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 2 |
Related Camptothecin Standards
- Camptothecin Impurity 10 (CAS 68426-53-9)
- Camptothecin Impurity 9 (CAS 67656-30-8)
- 7-Methyl Camptothecin (CAS 78287-26-0)
- (R)-(-)-Camptothecin-d5 (CAS 1329793-44-3)
- (S)-(+)-Camptothecin D5 (CAS 1329616-37-6)
- Camptothecin Impurity 16 (CAS 870527-52-9)
- 11-Ethyl Camptothecin (CAS 185807-29-8)
- Camptothecin Impurity 12 (CAS 19685-10-0)
Recommended Standards
- Irinotecan Hydrochloride Trihydrate EP Impurity B (CAS 19685-09-7)
- Serotonin Impurity 11 (CAS CATO-C4X-253411)
- N-[(1Z)-(Methoxyimino)methyl]-6-oxo-4-phenoxy-1-phenyl-1,6-dihydropyridazine-3-carboxamide (CAS 338405-13-3)
- Serotonin Impurity 13 (CAS 55747-60-9)
- Ceftazidime Impurity 45 (CAS 2647895-27-8)
- Pheniramine Impurity 2 (CAS 67168-93-8)
- Melatonin Impurity N2 (CAS 52450-39-2)
- 5-(3-Methoxypropyl)-1H-pyrazol-3-amine (CAS 884343-74-2)
- 2-{1,3-dimethyl-2,4-dioxo-1h,2h,3h,4h,7h-pyrrolo[2,3-d]pyrimidin-7-yl}acetic acid (CAS 950259-70-8)
- methylproline (CAS 68078-09-1)
- 3-Chloro-4-ethoxy-5-methoxybenzonitrile (CAS 749920-57-8)
- 2,6-Dimethoxy-3-methylsulfanylpyridine-5-boronic acid (CAS 2121512-34-1)
- 1-(5,6-Dichloropyridin-2-yl)ethanone (CAS 1211541-18-2)
- Semaglutide Impurity 145 (CAS CATO-C4X-2226145)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com