4-((2,4-Dimethoxybenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione CAS 677018-35-8
| CAS No. | 677018-35-8 |
| Molecular Formula | C17H15FN4O2S |
| Molecular Weight | 358.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-((2,4-Dimethoxybenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-((2,4-Dimethoxybenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 677018-35-8), a certified reference material (molecular formula C17H15FN4O2S, MW 358.39 g/mol) for analytical method development and quality control.
The molecular framework of 4-((2,4-Dimethoxybenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (C17H15FN4O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-((2,4-Dimethoxybenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H15FN4O2S |
| Molecular Weight | 358.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Dimethoxybenzylidene Standards
- 4-((2,3-Dimethoxybenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 578718-51-1)
- 4-((2,5-Dimethoxybenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 586994-98-1)
- 4-((3,4-Dimethoxybenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 585562-81-8)
- 3-(2-(2,5-Dimethoxybenzylidene)hydrazinyl)-6-methyl-5H-[1,2,4]triazino[5,6-b]indole (CAS 327032-34-8)
- 3-(5-(3,4-Dimethoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid (CAS 7025-25-4)
- 5-(2,4-Dimethoxybenzylidene)-2-phenylthiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 606960-78-5)
- 5-(3,4-Dimethoxybenzylidene)-2-phenylthiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 606949-54-6)
- 5-(3,4-Dimethoxybenzylidene)-2-(pyridin-4-yl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 606949-63-7)
Recommended Standards
- 3,4,2',4',6'- pentamethoxychalcone (CAS 76650-20-9)
- 3-(Benzyloxy)-5,5-diphenylimidazolidine-2,4-dione (CAS 26314-09-0)
- (+)-Epipinoresinol (CAS 24404-50-0)
- 3-(3-(4-((Pyridin-2-yloxy)methyl)benzyl)isoxazol-5-yl)pyridin-2-amine (CAS 936339-60-5)
- 6-Bromo-3-fluoro-N,N-bis(4-methoxybenzyl)-4-methylpyridin-2-amine (CAS 2803281-45-8)
- tert-butyl 4-(3-bromophenyl)-3-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate (CAS 1375303-50-6)
- 4-(Difluoromethyl)-6-methoxy-5-methylnicotinamide (CAS 1806862-68-9)
- N1-(quinolin-2-yl)ethane-1,2-diamine (CAS 137583-04-1)
- 4-Benzyl-5-(piperidin-1-ylmethyl)-4h-1,2,4-triazole-3-thiol (CAS 790263-73-9)
- 4-((tert-Butoxycarbonyl)amino)-3,5-dichlorobenzoic acid (CAS 915145-02-7)
- 4-Chloro-1-((2-fluorophenoxy)methyl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1006435-98-8)
- 2-Amino-3-methoxy-5-methylphenol (CAS 1823898-78-7)
- 2-(4-Bromophenyl)-1,1,1-trifluoropropan-2-ol (CAS 122243-28-1)
- Semaglutide Impurity 13 (CAS CATO-C4X-222613)
Why CATO?
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