Cetirizine EP Impurity E CAS 682323-77-9
| CAS No. | 682323-77-9 |
| Molecular Formula | C23H29ClN2O4 |
| Molecular Weight | 432.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Cetirizine EP Impurity E is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Cetirizine EP Impurity E (CAS 682323-77-9), a pharmacopoeial impurity reference standard (molecular formula C23H29ClN2O4, MW 432.94 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Cetirizine EP Impurity E is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 432.94 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Cetirizine EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H29ClN2O4 |
| Molecular Weight | 432.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Cetirizine Standards
- Cetirizine Dihydrochloride EP Impurity E (CAS CATO-C4X-108351)
- Cetirizine Impurity C127 (CAS 1391052-52-0)
- Cetirizine Impurity 17 (CAS CATO-C4X-158217)
- Cetirizine Impurity 30 (CAS CATO-C4X-158230)
- Cetirizine Impurity 29 (CAS 62084-35-9)
- Cetirizine Impurity 16 (CAS CATO-C4X-158216)
- Cetirizine impurity 31 (CAS CATO-C4X-158231)
- Cetirizine Impurity 39 (CAS CATO-C4X-108339)
Recommended Standards
- N-(2,4-dibromophenyl)benzohydrazonoyl bromide (CAS 2516-46-3)
- Cyproterone Acetate Impurity 2 (CAS 65423-26-9)
- Capivasertib-D4 (CAS CATO-C4X-331214)
- ARS-853 (CAS 1629268-00-3)
- Valproate Impurity 84 (CAS CATO-C4X-116684)
- Emedastine Impurity 49 (CAS CATO-C4X-226749)
- Itraconazole Impurity 66 (CAS 2570971-61-6)
- α-[[(Phenylmethoxy)carbonyl]amino]-1H-benzotriazole-1-acetic Acid (CAS 124676-19-3)
- Cyclopropyl-(5-isopropylpyridin-2-yl)-amine (CAS 1093955-11-3)
- 3-Methyl-5-(pentafluorosulfur)benzoic acid (CAS 1240257-00-4)
- 2-cyclopropyl-2-methoxypropan-1-ol (CAS 65080-60-6)
- 1-(Cyclopropylmethyl)-1h-benzo[d]imidazole-4-carboxylic acid (CAS 1547187-44-9)
- 3-Methyl-5-(3-methylphenyl)-5-oxovaleric acid (CAS 845781-36-4)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com