2-{[(2-chloro-1,3-thiazol-5-yl)methyl]sulfanyl}-4-(thiophen-2-yl)pyrimidine CAS 685107-87-3
| CAS No. | 685107-87-3 |
| Molecular Formula | C12H8ClN3S3 |
| Molecular Weight | 325.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-{[(2-chloro-1,3-thiazol-5-yl)methyl]sulfanyl}-4-(thiophen-2-yl)pyrimidine (CAS 685107-87-3), molecular formula C12H8ClN3S3 and molecular weight 325.86 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-{[(2-chloro-1,3-thiazol-5-yl)methyl]sulfanyl}-4-(thiophen-2-yl)pyrimidine (C12H8ClN3S3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-{[(2-chloro-1,3-thiazol-5-yl)methyl]sulfanyl}-4-(thiophen-2-yl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8ClN3S3 |
| Molecular Weight | 325.86 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 3 |
Related chloro Standards
- 7-Chloro-4-methyl-N-(3-morpholinopropyl)benzo[d]thiazol-2-amine (CAS 1105188-86-0)
- 5-Chloro-4-methyl-N-(3-morpholinopropyl)benzo[d]thiazol-2-amine (CAS 1204298-26-9)
- 6-Chloro-4-methyl-N-(3-morpholinopropyl)benzo[d]thiazol-2-amine (CAS 1350989-11-5)
- 2-[2-(6-Chloro-pyridazin-3-yl)-ethyl]-piperidine-1-carboxylic acid tert-butyl ester (CAS 1361112-59-5)
- 2-[2-(6-Chloro-pyrazin-2-yl)-ethyl]-piperidine-1-carboxylic acid tert-butyl ester (CAS 1361112-92-6)
- 4-[(6-Chloro-pyridazin-3-ylamino)-methyl]-piperidine-1-carboxylic acidtert-butyl ester (CAS 939986-36-4)
- 6-Chloro-N-(2-((4-fluorobenzyl)thio)-2-methylpropyl)pyridazin-3-amine (CAS 339104-47-1)
- 7-Chloro-4-(phenylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]thiazine (CAS 338778-00-0)
Recommended Standards
- Terbuchlor (CAS 4212-93-5)
- Acetamide, N-(butoxymethyl)-2-chloro-N-[2-ethyl-6-(1-methylethyl)phenyl]- (CAS 33717-34-9)
- 3-(4-Chlorophenyl)-N-isopropyl-5-(methylthio)thiophene-2-carboxamide (CAS 477857-94-6)
- Midazolam Impurity 28 (CAS CATO-C4X-150928)
- 2-(3-Fluoro-4-methoxyphenyl)cyclopentan-1-one (CAS 1340389-96-9)
- 3-((5-Methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)methoxy)benzaldehyde (CAS 1006460-23-6)
- 4-{[(cyclopropylmethyl)amino]methyl}phenol hydrochloride (CAS 1221722-75-3)
- 5-Ethyl-2-trifluoromethylpyrazine (CAS 1365969-77-2)
- 1-(2-(Pyrrolidin-1-yl)ethyl)-1H-benzo[d]imidazol-2-amine dihydrochloride (CAS 435342-19-1)
- 5-Amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-imidazole-4-carboxamide (CAS 23274-21-7)
- Ketoprofen Impurity 105 (CAS CATO-C4X-1471105)
- 1-(((1-Methoxypropan-2-yl)amino)methyl)cyclohexan-1-ol (CAS 1183437-74-2)
- 6,7-Dimethoxy-4-methylquinazolin-2-amine (CAS 21575-02-0)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
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