Midazolam Impurity 28 CAS CATO-C4X-150928
| CAS No. | CATO-C4X-150928 |
| Molecular Formula | C15H13ClFNS2 |
| Molecular Weight | 325.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Midazolam Impurity 28 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Midazolam Impurity 28 (CAS CATO-C4X-150928) is a certified pharmaceutical impurity reference standard with the molecular formula C15H13ClFNS2 and a molecular weight of 325.85 g/mol.
Structurally, Midazolam Impurity 28 (C15H13ClFNS2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 325.85 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Midazolam Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H13ClFNS2 |
| Molecular Weight | 325.85 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Midazolam Standards
- 【禁售不询】Midazolam (CAS 59467-70-8)
- Midazolam EP Impurity B (CAS 59469-74-8)
- Midazolam EP Impurity A (CAS 59468-07-4)
- Midazolam Impurity 40 (CAS CATO-C4X-150940)
- Midazolam EP Impurity J (CAS 59469-08-8)
- Midazolam-d5 (Major) Discontinued See M343003 (CAS 395067-42-2)
- Midazolam Impurity 23 (CAS CATO-C4X-150923)
- Midazolam Impurity 25 (CAS CATO-C4X-150925)
Recommended Standards
- Clemizole (CAS 442-52-4)
- 7-Chloro-4-methyl-N-(3-morpholinopropyl)benzo[d]thiazol-2-amine (CAS 1105188-86-0)
- Butanal, polymer with benzenamine (CAS 9003-37-6)
- 5-Chloro-4-methyl-N-(3-morpholinopropyl)benzo[d]thiazol-2-amine (CAS 1204298-26-9)
- Ensifentrine Impurity 21 (CAS CATO-C4X-335321)
- Moxifloxacin Impurity 58 (CAS CATO-C4X-107458)
- Estriol Impurity 27 (CAS 7219-89-8)
- (5-Bromo-2-chloropyridin-3-yl)methanamine (CAS 1211581-73-5)
- 6-Hydroxy-2-[2-(3-hydroxy-4-methoxyphenyl)ethenyl]-5-nitro-4(3H)-pyrimidinone (CAS 797779-25-0)
- 1-(Methoxymethyl)-1h-indol-6-amine (CAS 1493599-15-7)
- 4-Methylcycloheptane-1-sulfonyl chloride (CAS 1497198-55-6)
- 7-Bromo-2-methyl-1,2,3,4-tetrahydroisoquinoline-1,3-dione (CAS 1341602-23-0)
- 2-Chloro-6-ethoxypyridine-3-carboxylic acid (CAS 888740-54-3)
- Renin Inhibitor Peptide (CAS 50410-01-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com