Codeine Sulfate CII (250 mg) CAS 6854-40-6
| CAS No. | 6854-40-6 |
| Molecular Formula | 2*C18H21NO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Codeine Sulfate CII (250 mg).
Codeine Sulfate CII (250 mg) (CAS 6854-40-6) is a high-purity analytical reference standard with the molecular formula C18H21NO3H2O4SH2O and a molecular weight of 415.46 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Codeine Sulfate CII (250 mg) is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 415.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Codeine Sulfate CII (250 mg) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | 2*C18H21NO3 H2O4S 3*H2O |
| Molecular Weight | 415.46 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Codeine Standards
- Codeine-D6 (CAS 1007844-34-9)
- codeine hydrochloride (CAS 1422-07-7)
- Codeine β-D-Glucuronide Triacetate Methyl Ester (1.0mg/ml in Acetonitrile) (CAS 20736-10-1)
- Codeine-6β-D-glucuronide (CAS 20736-11-2)
- Codeine-6-ß-D-glucuronide-D3 (CAS 219533-59-2)
- Codeine 6-Methanesulfonate (1.0mg/ml in Acetonitrile) (CAS 22952-80-3)
- Codeine EP Impurity A (CAS 2859-16-7)
- Codeine Phosphate CII (1144000) (CAS 41444-62-6)
Recommended Standards
- (4R)-4-(trifluoromethyl)pyrrolidin-2-one (CAS 1431299-15-8)
- tert-Butyl 4-((benzylideneamino)methyl)piperidine-1-carboxylate (CAS 144222-21-9)
- Ethyl 5-(cyclohexyloxy)-1H-pyrazole-3-carboxylate (CAS 1344687-47-3)
- 2-Amino-4-(3,5-dimethyl-1h-1,2,4-triazol-1-yl)-2-methylbutanamide (CAS 1247735-86-9)
- Benzyl trans-4-amino-3-fluoropiperidine-1-carboxylate (CAS 1268520-05-3)
- 2-Chloromethyl-7-(trifluoromethyl)benzo[d]thiazole, 97% (CAS 1247348-75-9)
- 2-[1-(1,1-Dioxido-1,2-benzisothiazol-3-yl)-hydrazino]ethanol (CAS 312500-56-4)
- (2E)-1-(2-Chlorophenyl)-3-(3-methylphenyl)prop-2-en-1-one (CAS 1354942-01-0)
- (S)-N,N-dimethyl-2-(pyrrolidin-2-yl)ethan-1-amine (CAS 1315359-43-3)
- Ac-(5-31)Semaglutide (CAS CATO-C4X-2226279)
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