Acipimox Impurity 11 CAS 6890-38-6
| CAS No. | 6890-38-6 |
| Molecular Formula | C6H8N2O2 |
| Molecular Weight | 140.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 140.14 g/mol gives Acipimox Impurity 11 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Acipimox Impurity 11 (CAS 6890-38-6, C6H8N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Acipimox Impurity 11 (C6H8N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Acipimox Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8N2O2 |
| Molecular Weight | 140.14 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Acipimox Standards
Recommended Standards
- Minoxidil Impurity 7 (CAS 3270-97-1)
- Etomidate Impurity 6 (CAS 23785-21-9)
- Butenafine Impurity 12 (CAS 88-03-9)
- Phloroglucinol Impurity 29 (CAS 2174-64-3)
- Topiroxostat Impurity 16 (CAS CATO-C4X-105516)
- Vericiguat Impurity 19 (CAS 2112745-90-9)
- Mivacurium chloride Impurity 37 (CAS 91248-14-5)
- 2,4,8-Trimethylquinoline (CAS 18441-61-7)
- Etoricoxib impurity 56 (CAS 646459-51-0)
- 1-((4-Chloro-1H-pyrazol-1-yl)methyl)-3,5-dimethyl-1H-pyrazol-4-amine (CAS 1006473-09-1)
- 5-(Triethoxysilyl)thiazole (CAS 1243360-03-3)
- Pictilisib (GDC-0941) (CAS 957054-30-7)
- 1-Benzyl-5-methyl-3-nitro-1h-pyrazole (CAS 898053-54-8)
- Palmitoyl Tripeptide-1 TFA salt (CAS 2803375-47-3)
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