Cytarabine hydrochloride CAS 69-74-9
| CAS No. | 69-74-9 |
| Molecular Formula | C9H13N3O5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Cytarabine hydrochloride (CAS 69-74-9), molecular formula C9H13N3O5HCl and molecular weight 279.68 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Cytarabine hydrochloride (C9H13N3O5HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 279.68 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Cytarabine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H13N3O5 HCl |
| Molecular Weight | 279.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Cytarabine Standards
- Cytarabine Impurity 26 (CAS 10212-22-3)
- Cytarabine EP Impurity H HCl (CAS 10212-25-6)
- Cytarabine Impurity 38 (CAS 104105-73-9)
- Cytarabine Impurity 28 (CAS 13491-47-9)
- Cytarabine Impurity 2 (CAS 14057-18-2)
- Cytarabine (CAS 147-94-4)
- Cytarabine Impurity 31 (CAS 169687-80-3)
- Cytarabine EP Impurity G (CAS 2140-61-6)
Recommended Standards
- 3-((Tert-butoxycarbonyl)amino)bicyclo[2.1.0]Pentane-1-carboxylic acid (CAS 2387220-99-5)
- 2-Formyl-4,5-dimethoxyphenylboronic Acid (CAS 1005346-96-2)
- N-[2-(2-Chlorophenoxy)ethyl]-3-(trifluoromethyl)aniline (CAS 1040685-01-5)
- [4'-(Benzyloxy)[1,1'-biphenyl]-4-yl]methanol (CAS 214978-34-4)
- 3-(Tert-butyl)-1-methyl-4-nitro-1H-pyrazole-5-carbaldehyde (CAS 817172-31-9)
- H-Cys(Trt)-OtBu (CAS 76587-61-6)
- (1Z)-n′,3-dihydroxypropanimidamide (CAS 53370-50-6)
- 2,2-Difluoro-2-(3-methoxypyridin-2-yl)acetic acid (CAS 1698403-23-4)
- methyl 2-methyl-4-oxo-5H-pyrrolo[1,2-a]quinoxaline-8-carboxylate (CAS 2768550-22-5)
- Peptide Impurity 15 (CAS 1227750-69-7)
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