5-Hydroxy Diclofenac CAS 69002-84-2
| CAS No. | 69002-84-2 |
| Molecular Formula | C14H11Cl2NO3 |
| Molecular Weight | 312.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Hydroxy Diclofenac.
5-Hydroxy Diclofenac (CAS 69002-84-2), molecular formula C14H11Cl2NO3 and molecular weight 312.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Hydroxy Diclofenac (C14H11Cl2NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11Cl2NO3 |
| Molecular Weight | 312.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- 4'-Hydroxy Diclofenac (CAS 64118-84-9)
- 2-(5-(Hydroxy((3-hydroxy-2,3-dimethylbutan-2-yl)oxy)boranyl)-2-methyl-1H-imidazol-1-yl)ethyl acetate (CAS 1402166-63-5)
- Sodium 2- (hydroxy) (sulfonyl) methyl) benzenesulfonate (CAS CATO-C3D-262161)
- Methyl 6-hydroxy-2'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxylate (CAS 1261659-28-2)
- Methyl 6-hydroxy-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxylate (CAS 1261855-31-5)
- 5-Hydroxy Flunixin (CAS 75369-61-8)
- 5-Hydroxy-7-(3-(trifluoromethyl)phenyl)benzo[d][1,3]oxathiol-2-one (CAS 405921-10-0)
- 10-Hydroxy-5,9-dimethoxy-2H-pyrano[2,3,4-kl]xanthen-2-one (CAS 112078-70-3)
Recommended Standards
- Diclofenac Impurity 42 (CAS 944251-06-3)
- Methyl 5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole-4-carboxylate (CAS 946426-88-6)
- Diclofenac Impurity 44 (CAS 69002-85-3)
- Methyl 5-chloro-1-[(4-chlorophenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxylate (CAS 400087-49-2)
- (4-(MEthoxycarbonyl)-phenyl) zinc pivalate (CAS 1383708-41-5)
- 4-Bromo-2-methyl-5-((1-(thiophen-3-yl)propan-2-yl)amino)pyridazin-3(2h)-one (CAS 1355519-58-2)
- 1,5-Bis(cyclopentylamino)anthracene-9,10-dione (CAS 719306-64-6)
- methyl 2,4-bis(difluoromethoxy)benzoate (CAS 97914-57-3)
- Tert-butyl (3S,4S)-3-(aminomethyl)-4-(4-methyloxazol-5-yl)pyrrolidine-1-carboxylate (CAS 2351239-05-7)
- 4-Bromo-3-methylbenzimidamide (CAS 202805-69-4)
- ethyl 2-[(chloroacetyl)amino]thiophene-3-carboxylate (CAS 648859-97-6)
- 4-Methylpyridine-3-boronic acid pinacol ester, 97% (CAS 1171891-31-8)
- 3-Amino-4-cyclopentyl-2-hydroxybutanamide hydrochloride (CAS 914072-55-2)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
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