Diclofenac Impurity 42 CAS 944251-06-3
| CAS No. | 944251-06-3 |
| Molecular Formula | C14H11Cl2NO3 |
| Molecular Weight | 312.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Diclofenac Impurity 42.
As a process- or degradation-related impurity, Diclofenac Impurity 42 (CAS 944251-06-3, C14H11Cl2NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C14H11Cl2NO3, Diclofenac Impurity 42 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 312.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Diclofenac Impurity 42 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H11Cl2NO3 |
| Molecular Weight | 312.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Diclofenac Standards
- Diclofenac Impurity 44 (CAS 69002-85-3)
- Diclofenac Impurity 23 (CAS CATO-C4X-105123)
- Diclofenac Methyl Ester (Aceclofenac EP Impurity B) (CAS 15307-78-5)
- Diclofenac sodium Impurity 48 (CAS 66156-75-0)
- Diclofenac Related Compound 1 (CAS 928343-25-3)
- Diclofenac sodium Impurity 63 (CAS 1254576-93-6)
- Diclofenac impurity f (CAS 124426-56-8)
- Diclofenac sodium Impurity 37 (CAS 15308-01-7)
Recommended Standards
- 5-Hydroxy Diclofenac (CAS 69002-84-2)
- 4'-Hydroxy Diclofenac (CAS 64118-84-9)
- Ornidazole Impurity 69 (CAS CATO-C4X-133169)
- Methyl 5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole-4-carboxylate (CAS 946426-88-6)
- Benzocaine Impurity 31 (CAS 71134-95-7)
- Ixazomib Impurity 50 (CAS 220315-20-8)
- Linagliptin impurity 140 (CAS 2428491-17-0)
- Methyl 4-Oxo-1-(2,4,5-trifluorophenyl)cyclohexanecarboxylate (CAS 1385694-46-1)
- 4-Carbomethoxy-cyclohexane-1-carboxylic acid (CAS 32529-79-6)
- cis-3-Cyano-3-fluorocyclobutanecarboxylic acid (CAS 2471973-37-0)
- 3-Amino-5-chloropicolinaldehyde (CAS 1289046-39-4)
- Ethyl 4-((4-((3-carbamoyl-6-isopropyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)carbamoyl)phenyl)sulfonyl)piperazine-1-carboxylate hydrochloride (CAS 1215664-62-2)
- 2-(4-Aminophenyl)-6-bromo-8-methylquinoline-4-carboxylic acid (CAS 1160264-26-5)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com