2,4-Bis(5-iodo-1H-indol-1-yl)butane-1,3-diol CAS 690266-56-9
| CAS No. | 690266-56-9 |
| Molecular Formula | C20H18I2N2O2 |
| Molecular Weight | 572.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2,4-Bis(5-iodo-1H-indol-1-yl)butane-1,3-diol (CAS 690266-56-9), molecular formula C20H18I2N2O2 and molecular weight 572.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,4-Bis(5-iodo-1H-indol-1-yl)butane-1,3-diol (C20H18I2N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H18I2N2O2 |
| Molecular Weight | 572.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- Isopropyl (3-chloro-5-(1-((6-(2-(5-ethyl-4-methylthiazol-2-yl)ethyl)-4-morpholinopyridin-2-yl)amino)ethyl)phenyl)carbamate (CAS 329716-61-2)
- Montelukast Impurity 4 (CAS 1772578-77-4)
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- Crisaborole Impurity 145 (CAS CATO-C4X-2021145)
- (R)-1-(2-Fluoro-4-methylphenyl)ethanamine hydrochloride (CAS 2301881-38-7)
- 2-(1H-pyrazol-1-yl)phenol hydrobromide (CAS 1803562-27-7)
- 2-(3-Hydroxyphenyl)quinoline-4-carboxylic acid (CAS 32366-58-8)
- (R)-1-(4-(difluoromethoxy)phenyl)ethan-1-amine (CAS 856758-57-1)
- 8-quinolinolium 4,7-dibromo-3-hydroxy-2-naphthoate, Copper (ii) Salt (CAS 63717-34-0)
- 4-(2,4-Dichlorobenzoyl)-N'-[2-(2,4-dichlorophenoxy)ethanimidoyl]-1-methyl-1H-pyrrole-2-carbohydrazide (CAS 338395-71-4)
- 2-(4-Methylpiperidin-1-yl)-1,3-thiazole-5-carboxylic acid (CAS 1341104-73-1)
- 2-(2-Bromoethyl)-5-methoxypyridine (CAS 1260663-55-5)
- methyl (2R,8S)-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizine-8-carboxylate (CAS 2891580-45-1)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
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