Lodoxamide lmpurity 12 CAS 69236-82-4
| CAS No. | 69236-82-4 |
| Molecular Formula | C7H7ClN2O2 |
| Molecular Weight | 186.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Lodoxamide lmpurity 12 (CAS 69236-82-4) is a certified pharmaceutical impurity reference standard with the molecular formula C7H7ClN2O2 and a molecular weight of 186.60 g/mol.
Based on its molecular formula C7H7ClN2O2, Lodoxamide lmpurity 12 contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 186.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7ClN2O2 |
| Molecular Weight | 186.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Lodoxamide Standards
- Lodoxamide lmpurity 11 (CAS 67451-38-1)
- Lodoxamide lmpurity 10 (CAS 34207-46-0)
- Lodoxamide lmpurity 9 (CAS 61313-43-7)
- Lodoxamide impurity 24 (CAS 27697-45-6)
- Lodoxamide Impurity 2 (CAS 55441-26-4)
- Lodoxamide lmpurity 17 (CAS 84944-23-0)
- Lodoxamide Impurity 3 (CAS 617-36-7)
- Lodoxamide Impurity 6 (CAS 75235-35-7)
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