Captopril Impurity 31 CAS 69570-39-4

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.69570-39-4
Molecular FormulaC6H9ClO2S
Molecular Weight180.65 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Captopril Impurity 31 CAS 69570-39-4 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Captopril Impurity 31 (CAS 69570-39-4) is a certified pharmaceutical impurity reference standard with the molecular formula C6H9ClO2S and a molecular weight of 180.65 g/mol.

Structurally, Captopril Impurity 31 (C6H9ClO2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 180.65 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC6H9ClO2S
Molecular Weight180.65 g/mol
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityContains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1976
Halogen ContentCl-containing
Sulfur Atoms1

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