Alvimopan Impurity 2 CAS 6967-88-0
| CAS No. | 6967-88-0 |
| Molecular Formula | C9H11BrO |
| Molecular Weight | 215.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Alvimopan Impurity 2 (CAS 6967-88-0), a pharmacopoeial impurity reference standard (molecular formula C9H11BrO, MW 215.09 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Alvimopan Impurity 2 (C9H11BrO) is characterized by a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H11BrO |
| Molecular Weight | 215.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Br-containing |
Related Alvimopan Standards
- Alvimopan Impurity 1 (CAS 701-07-5)
- Alvimopan Impurity 27 (CAS 119193-19-0)
- Alvimopan Impurity 28 (CAS 145678-87-1)
- Alvimopan Impurity 12 (CAS 1980007-99-5)
- Alvimopan Impurity N12 (CAS 59381-63-4)
- Alvimopan Impurity 18 (CAS 145340-45-0)
- Alvimopan Impurity 20 (CAS 1314751-83-1)
- Alvimopan impurity 15 (CAS CATO-C4X-114515)
Recommended Standards
- Anastrozole Impurity 29 (CAS CATO-C4X-123929)
- ((2-Bromoethoxy)methyl)benzene (CAS 1462-37-9)
- iotropium Bromide Impurity 12 (CAS 588-63-6)
- 86623-33-8 Benzene, (2-bromo-1-methylethoxy)- (CAS 86623-33-8)
- Losartan Impurity 15 (CAS 114772-55-3)
- Nicotinamide impurity 23 (CAS CATO-C4X-200023)
- Donepezil Impurity 25 (CAS 120012-04-6)
- Isothiazolo[4,3-b]pyridin-3-ylamine (CAS 42242-13-7)
- tert-Butyl 5-chloro-6-fluoronicotinate (CAS 211122-62-2)
- 1-(2-Chloro-4-nitrophenyl)-3-(1,3-dioxan-2-yl)propan-1-one (CAS 937040-35-2)
- (R)-4-(tert-butoxycarbonyl)-2,2-dimethylmorpholine-3-carboxylic acid (CAS 1416444-90-0)
- RGFP 109 (CAS 1215493-56-3)
- 1-Bromobutane-4,4,4-d3 (CAS 55724-42-0)
- Semaglutide impurity 22(OtBu-Ste-γGlu(OtBu)-AEEA-AEEA-OH) (CAS 1118767-16-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com