Isothiazolo[4,3-b]pyridin-3-ylamine CAS 42242-13-7
| CAS No. | 42242-13-7 |
| Molecular Formula | C6H5N3S |
| Molecular Weight | 151.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 151.19 g/mol gives Isothiazolo[4,3-b]pyridin-3-ylamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Isothiazolo[4,3-b]pyridin-3-ylamine (CAS 42242-13-7) is a high-purity analytical reference standard with the molecular formula C6H5N3S and a molecular weight of 151.19 g/mol.
The molecular framework of Isothiazolo[4,3-b]pyridin-3-ylamine (C6H5N3S) is characterized by a nitrile group, sulfur-containing functionality, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Isothiazolo[4,3-b]pyridin-3-ylamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5N3S |
| Molecular Weight | 151.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Isothiazolo Standards
- Isothiazolo[4,5-c]pyridin-3-amine (CAS 1367990-09-7)
- Isothiazolo[3,4-c]pyridin-3-amine (CAS 150364-74-2)
- Isothiazolo[5,4-c]pyridin-3-amine (CAS 150364-77-5)
- Isothiazolo[4,5-b]pyridin-3-amine (CAS 2089325-25-5)
- Isothiazolo[5,4-b]pyridin-3-amine (CAS 56891-64-6)
- Isothiazolo[5,4-b]pyridin-3-ol (CAS 4337-60-4)
- Isothiazolo[4,5-b]pyrazin-3-amine (CAS 92914-68-6)
- Isothiazolo[5,4-d]pyrimidin-4-ol (CAS 1498711-48-0)
Recommended Standards
- Imidazo[1,5-a]pyrazine-8-thiol (CAS 746547-06-8)
- Imidazo[1,5-a]pyrazine-3(2H)-thione (CAS 56488-16-5)
- Imidazo[1,2-a]pyrazine-6-thiol (CAS 763916-91-2)
- Thiazolo[3,2-a]pyridin-4-ium-3-olate (CAS 42715-25-3)
- [2-(2,6,7-Trimethyl-1H-indol-3-yl)ethyl]amine dihydrate (CAS 1609401-31-1)
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- 1-(2,2,2-trifluoro-1-methyl-ethyl)piperazine;dihydrochloride (CAS 2411640-32-7)
- Peptide WE-14 (CAS 115136-18-0)
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