Progesterone Impurity N38 CAS 70081-51-5
| CAS No. | 70081-51-5 |
| Molecular Formula | C21H28O4 |
| Molecular Weight | 344.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Progesterone Impurity N38 (CAS 70081-51-5) is a certified pharmaceutical impurity reference standard with the molecular formula C21H28O4 and a molecular weight of 344.44 g/mol.
Structurally, Progesterone Impurity N38 (C21H28O4) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 344.44 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H28O4 |
| Molecular Weight | 344.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
Related Progesterone Standards
- Progesterone Impurity N3 (CAS 5327-60-6)
- Progesterone Impurity 46 (CAS CATO-C4X-150246)
- Progesterone Impurity 52 (CAS 14508-05-5)
- Progesterone Impurity 65 (CAS CATO-C4X-150265)
- Progesterone Impurity 69 (CAS CATO-C4X-150269)
- Progesterone Impurity 81 (CAS CATO-C4X-150281)
- Progesterone Impurity 85 (CAS 151122-70-2)
- Progesterone Impurity 17 (CAS 20248-18-4)
Recommended Standards
- 4-Acetoxy-4-androstene-3,17-dione (CAS 61630-32-8)
- 6β,17-Dihydroxy-pregna-1,4-diene-3,20-dione (CAS 95042-81-2)
- ∆8-Tetrahydro Cannabinol-11-oic Acid (CAS 39690-06-7)
- Corticosterone Impurity 3 (CAS 2681-57-4)
- Methylprednisolone Impurity 3 (CAS CATO-C4X-19193)
- Lacosamide EP Impurity C (CAS CATO-C4X-183049)
- Artesunate Impurity 4 (CAS CATO-C4X-15474)
- 1797131-66-8 2-Chloro-8-methoxy-dibenz[b,f][1,4]oxazepin-11(10H)-one (CAS 1797131-66-8)
- 2-(5-Oxo-4-(p-tolyl)-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetonitrile (CAS 866149-37-3)
- 4-Bromo-2-(cyclopentyloxy)anisole (CAS 138509-45-2)
- 3-Fluoro-2-methoxybenzoyl chloride (CAS 106428-06-2)
- 16089-63-7 CTK0E6613 Methanamine, N-[(4-methylphenyl)methylene]-, N-oxide (CAS 16089-63-7)
- Fmoc-(3,(Pbf)Guanidino)-Ala-OH (CAS 1313054-86-2)
- Ganirelix 1-4 peptide (CAS 208599-57-9)
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